BACKGROUND Despite radical surgical and chemotherapeutic treatment of ovarian cancer, the majority of patients develop recurrence and die due to progressive disease. Routine measurement of the tumor marker CA-125 is often used in the follow-up management. However, the role of preoperative CA-125 as a prognostic factor before secondary cytoreduction of relapsed ovarian cancer has not been determ...

Dear Editor: I have read with interest the article published by Ozsahin et al. (1) focused on the validity of the cancer antigen-125 (CA-125) in the differential diagnosis of active pulmonary tuberculosis (TB). In accordance with a previous study by Yilmaz et al. (2), they reported higher serum CA125 levels in active pulmonary TB than in inactive pulmonary TB. However, the authors found lower s...

PURPOSE Previous studies have shown that elevated preoperative serum CA 125 levels strongly correlate with various clinical and pathological variables and prognosis of patients with endometrial carcinoma (EC). The aim of the present study was to evaluate the clinical significance of preoperative serum CA 125 levels in patients with EC. METHODS A retrospective study of all EC patients treated ...

Understanding of the relationship between tumor infiltrating cytotoxic T lymphocytes (CD 8(+)TILs) and tumor cells as well as tumor-associated antigens is important and may reflect the extent of immune response of the patient to the tumor, thus providing a useful clue relevant to the prognosis. The purpose of this study was to determine the relationship between the expression of HLA-DR and CA-1...

OBJECTIVE Meigs' syndrome presenting as an ovarian tumor with elevated serum cancer antigen 125 (CA 125) levels is unusual. Only 37 cases have been reported, including three cases of ovarian sclerosing stromal tumor (SCT). Many reports have suggested that the presence of ascites is the major factor inducing mesothelial expression of CA 125. CASE REPORT An 18-year-old woman presented with mass...

were stained by the same antibody; they were mature eosinophils with segmented nuclei. In a bone marrow biopsy specimen from a patient with hypereosinophilic syndrome, there were also many mature EG2-positive eosinophils. These observations suggest that in asthma eosinophils have already been activated in the early immature stage in the bone marrow. This finding might be related to the pathogen...

OBJECTIVE To analyze the clinical effect of laparoscopy on patients with endometriosis and a high expression of CA125. PATIENTS AND METHODS One hundred cases of endometriosis treated in our hospital from May 2012 to August 2014 were selected as research subjects, after approval from the hospital and the informed consent of patients. The subjects were randomly divided into a control group and ...

Ovarian cancer is difficult to manage because the disease is most often diagnosed at an advanced stage when survival chances are poor. Early detection of ovarian cancer would increase long-term survival, since effective treatment modalities are available for early-onset disease. Screening with transvaginal ultrasound and serum CA 125 suggests promising results, but studies comparing mortality r...

BACKGROUND Cancer antigen 125 (CA 125), a widely used tumor marker for monitoring epithelial ovarian cancer, is also found to be raised in non-gynecological tumors and non malignant disease involving peritoneum. We report a case of non-Hodgkin's lymphoma who presented with peritoneal and pleural effusions with a very high level of serum CA 125. CASE Fifty four years female presented with gros...

AIMS The aim of this study was to evaluate the relationship between pathological findings and clinical features in patients with ovarian mature cystic teratomas (MCTs). MATERIALS AND METHODS We reviewed and compared the demographic and clinical features of 32 patients confirmed pathologically as having MCT at a university hospital from 2009 to 2014, with MCT contents such as skin, hair, sebum...