Caffeine, dose dependently can reinforce or deteriorate learning. In previous studies, the effect of glucose on decreasing of amnesia was investigated. In this study, the effect of caffeine on three phases of learning and also probable interference of glucose in mice were examined by using of passive avoidance learning .Male albino mice were examined as follows: 1. test group: a) this group rec...

There is a great call for using microbial bio-decaffeination approach to remove caffeinefrom caffeinated products and industrial wastes. We aimed in this study to screen strainsof yeasts which exhibit high caffeine tolerance and to investigate the bio-degradation ofcaffeine under growth conditions. Sixteen yeast strains were isolated from the cultivatedtea soils collected from sites of northern...

In this work, we studied the biosynthesis of caffeine by examining the expression of genes involved in this biosynthetic pathway in coffee fruits containing normal or low levels of this substance. The amplification of gene-specific transcripts during fruit development revealed that low-caffeine fruits had a lower expression of the theobromine synthase and caffeine synthase genes and also contai...

Caffeine is a natural substance present in leaves and seeds of many plants. The aim of this study is to evaluate the caffeine level in the carbonated drinks from the Romanian market. For this survey were taken 30 samples of different carbonated drinks. The caffeine was determined and quantified using a HPLC with diode array detector at 206 nm. The caffeine retention time was at 17.785 minutes. ...

Caffeine and Stroke To the Editor: Several investigators have recently shown that rodents chronically given caffeine develop upregulation of adenosine receptors and tolerate brain ischemia better than rodents not given caffeine.'The upregulation results from caffeine's action as a competitive antagonist of adenosine. These findings provide further evidence for a neuroprotective effect of adenos...

Spontaneous contractions of liver fluke muscle were abolished in Ca2+-free saline and by 100 μM nifedipine and reduced by 5 mM cadmium chloride, suggesting that they are dependent on extracellular Ca2+. Caffeine (5 mM) significantly increased contraction amplitude and frequency. Ryanodine (100 μM) failed to block the caffeine response but significantly reduced spontaneous contraction frequency,...

Research into the cognitive and mood effects of caffeine in human subjects has highlighted some fairly robust and well-accepted effects. However, the majority of these studies have focused on caffeine in isolation; whilst caffeine is normally consumed in the form of plant-derived products and extracts that invariably contain other potentially bioactive phytochemicals. The aim of the present rev...

AIM The aim of this study was to evaluate the effect of caffeine on collagen biosynthesis in human skin fibroblasts and the influence of hyaluronic acid (HA) on this process. MATERIALS AND METHODS Collagen, [(3)H]-thymidine incorporation, and prolidase activity were measured in confluent human skin fibroblast cultures that had been treated with 1, 2, and 5 mM caffeine and with caffeine and 50...