Abstract BLOC1S1 is an adaptor protein that modulates endosome-lysosome function as a component of numerous multiprotein complexes. We postulated its modulation in CD4 +T cells may help us uncover the role biology adaptive immunity. In primary cre-recombinase knockout resulted preferential induction Th2 compared to Th1 and Th17 cytokine production following T cell receptor activation. As atopic...