Aim: The inhibitory effect of the root of Ichnocarpus frutescens on nephrolithiasis induced in rats by feeding with ethylene glycol water (0.75%) for 28 days was summarized. Method: Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate. Results: Supplementation with ethyle acetate extract of Ichnocarpus frutescens significantly reduced t...

Bergsland, Kristin J., Jennifer K. Kelly, Brian J. Coe, and Fredric L. Coe. Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers. Am J Physiol Renal Physiol 291: F530–F536, 2006. First published April 18, 2006; doi:10.1152/ajprenal.00370.2005.—We have investigated urine protein inhibitors of calcium oxalate crystallization to determine whethe...

Abstract Residual fragments can remain after kidney stone extraction which may necessitate another intervention. Magnetic nanoparticles (MNP) be applied due to their properties of being able bind residual and extracted by an external magnetic field. Calcium oxalate crystals have been synthesized, characterized used for binding separation studies. The is validated simulation experimentally. MNP ...

Urine contains compounds that modulate the nucleation, growth and aggregation of crystals as well as their attachment to renal epithelial cells. These compounds may function to protect the kidneys against: 1, the possibility of crystallization in tubular fluid and urine, which are generally metastable with respect to calcium salts, 2, crystal retention within the kidneys thereby preventing ston...

BACKGROUND AND OBJECTIVES Medullary sponge kidney (MSK) is a renal malformation typically associated with nephrocalcinosis and recurrent calcium stones. Incomplete distal renal tubular acidosis, hypocitraturia, and hypercalciuria are common. For stone prevention, patients with MSK generally receive the standard "stone clinic" recommendations and often receive potassium citrate (KC). However, th...

Two issues related to nephrolithiasis are explored: (1) does the chemical composition and morphology of renal calculi in South Poland overlap with the studies from other countries? and (2) are there possibilities to evaluate in vivo chemical composition of stones using computed tomography? The study was conducted on 108 renal stones. X-ray fluorescence, X-ray diffraction and Fourier transformed...

PURPOSE To evaluate a physician's impression of a urinary stone patient's dietary intake and whether it was dependent on the medium through which the nutritional data were obtained. Furthermore, we sought to determine if using an electronic food frequency questionnaire (FFQ) impacted dietary recommendations for these patients. MATERIALS AND METHODS Seventy-six patients attended the Stone Clin...

BACKGROUND AND OBJECTIVES Sodium thiosulfate (STS) reduced calcium stone formation in both humans and genetic hypercalciuric stone forming (GHS) rats. We sought to measure urine chemistry changes resulting from STS administration in people. DESIGN SETTING PARTICIPANTS MEASUREMENTS: STS was given to healthy and hypercalciuric stone forming adults. Five normal non-stone forming adults (mean age 3...

Since incidence of idiopathic calcium oxalate urolithiasis in children was very low, a study was made to analyze the risk factors of calcium oxalate stone in male volunteers without any episode of urolithiasis. They were divided into four groups, group I: eight years old, group II: 11 years old, group III: 18 to 24 years old, group IV: 41 to 45 years old. Inhibitory activities of urine were sig...

PURPOSE We compared the effect of 3 animal protein sources on urinary stone risk. MATERIALS AND METHODS A total of 15 healthy subjects completed a 3-phase randomized, crossover metabolic study. During each 1-week phase subjects consumed a standard metabolic diet containing beef, chicken or fish. Serum chemistry and 24-hour urine samples collected at the end of each phase were compared using m...