نتایج جستجو برای: cancer cell
تعداد نتایج: 2332371 فیلتر نتایج به سال:
compounds containing triazene ring structure are cytotoxic agents and clinically used as antitumor alkylating agents. in this study, a series of triazene derivatives holding alkyl and aryl moieties were synthesized and proved to be potent cytotoxic agents in-vitro particularly against eight cancer cell lines (pc3, ht29, hela, hl60, jurkat, k562, mcf7, hepg2) and a non-cancerous cell line (huvec...
Esophageal cancer (EC) is the sixth main cause of cancer death worldwide. Important genes associated with esophageal cancer include FOXO3, AKT, and GSK3β. Excessive FOXO3 expression inhibits the proliferation of cancer cells. The expression of AKT is involved in controlling cell growth in tumors. GSK3β activity is higher in cancer tissues. Given the effective role of cancer stem cells (CSCs) in...
Objective(s):Multidrug resistance (MDR) of cancer cells is a major obstacle to successful chemotherapy. Overexpression of breast cancer resistance protein (BCRP) is one of the major causes of MDR. In addition, it has been shown that PI3K/Akt signaling pathway involves in drug resistance. Therefore, we evaluated the effects of novel approaches including siRNA directed against BCRP and targeted t...
Cytotoxic Effect of Hydroalcoholic Extract from Satureja bachtiarica Bunge on Hela Cancer Cells Line
Background & Aim:Cervical cancer is the most common female genital cancer and the second most common cancer in women in the world. Since the herbal ingredients have been used for centuries to treat cancer, purpose of the present study was to determine the cytotoxic effect of hydroalcoholic extract from Satureja bachtiarica Bungeon Hela cancer cells line. ...
Bleomycin (BLM) as an anti-cancer agent causes tissue toxicities through DNA damaging and cell deaths. The aim of this study was to investigate the effects of thymol against genotoxicity and anti-proliferation induced by BLM in normal human lymphocytes and ovarian cancer cells. Peripheral blood samples were collected from human volunteers and were incubated with thymol at different concentratio...
Background: Prostate cancer is one of the leading causes of cancer deaths among men. New gene expressed in prostate (NGEP), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. Because of its selective expression in prostate cancer cell surface, NGEP is a potential immunotherapeutic target. To target the NGEP in prostate cancer, it is essential to investig...
Background[d1] and Objective: Cancer is a prevalent disease that occurs due to genetic and environmental factors. Gastric cancer is one of the most common cancers around the world and also in Iran. N. sativa has been used as a drug in the treatment of many diseases owing to its valuable secondary metabolites such as thymoquinone. In this study, the anti-cancer properties of black seed extract...
it has been observed that lung cancer either non-small cell or small cell is responsible for eye metastases. this form of metastases in several cases was the first manifestation of the disease and further investigation led to the diagnosis of the underlying malignancy. both types of lung cancer are equally responsible for this demonstration. furthermore; both chemotherapy and tyrosine kinase in...
Parthenolide is major Sesquiterpene lactones present in Anthemis haussknechtii Boiss. & Reut. (feverfew). This compound has many effects on different disease such as migrain and cancer. Parthenolide was reported from Tanacetum parthenium (L.) Sch.Bip. but other plants of Asteraceae family could contain parthenolide. In this study parthenolide was extracted and identified with two methods, Fouri...
Background and Objective: Breast cancer is the most common cancer among women worldwide. Saffron is one of the most well-known plants as an antioxidant and anticancer. The aim of this study was to assess the impact of saffron on the viability of breast cancer cells and simultaneous interaction effect of Paclitaxel drug. Materials and Methods: In this study, saffron extract (Crocus sativus L.) w...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید