The successful therapy strategy of gastric cancer is defined as devastating of the cancerous cells without exposing systematic toxicity and undesirable side effects. One strategy to overcome cancer treatment related difficulties could be combination therapy with natural products with anticancer drugs to introduce effective antitumor effects in addition to reduction of undesirable side effects. ...

Platinum is a metallic element, which may react with our cellular component through its involvement in cancer chemotherapy medications. Cisplatin is one of the most useful antineoplastic drugs against human ovarian carcinoma, which has the central element of platinum in its structure. The nature of chemical interaction between platinum and cellular macromolecules is yet to be understood. We exa...

INTRODUCTION There are major differences in cancer drug prices around the world. However, the patterns of affordability of these drugs are poorly understood. The objective of this study was to compare patterns of affordability of cancer drugs in Australia, China, India, Israel, South Africa, the United Kingdom, and the United States. RESULTS Cancer drug prices are highest in the United States...

Paralytic ileus is a condition where the intestine becomes paralysed in absence of any mechanical obstruction. The common causes are intra-abdominal surgery, severe metabolic problems and drugs. Many anticancer drugs targeted therapy important this toxicity. Early diagnosis appropriate management essential because if prolonged untreated it can lead to death same way as acute Capecitabine an ora...

Purpose: In this study, we evaluated the analgesic potential of demethylating drugs on oral cancer pain. Althoughdemethylating drugs could affect expressionofmany genes,we focused on themu-opioid receptor (OPRM1) gene pathway, because of its role in pain processing. We determined the antinociceptive effect of OPRM1 re-expression in a mouse oral cancer model. Experimental Design: Using a mouse o...

Cancer is among the leading causes of death worldwide and therefore one diseases in which there have been major medical advances focus researchers. Drugs used cancer treatment affect rapidly proliferating normal cells as well cells. In recent years, targeted therapy has provided by identifying specific pathways Epigenetic mechanisms are therapies treatment. regulators ensure continuity process ...

Small Cell Lung Cancer (SCLC) is a low-differentiated neuroendocrine tumor with rapid growth, early metastasis and sensitivity to radiotherapy chemotherapy. It highly recurrence rate. And there lacking effective treatment now. As an active research direction at present, anti-angiogenic drugs are not only widely used in non-small cell lung cancer other tumors, but also have certain effects small...