Background and Objectives: Involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. In the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied issue. The aim of this study was determination of the relationship between the size of col...

a member of homeodomain protein namely tgif2lx has been implicated as a tumor suppressor gene in human malignancy as well as in spermatogenesis. however, to our knowledge, dynamic functional evidence of the tgif2lx has not yet been provided. the aim of the present study was to investigate the human tgif2lx target gene(s) using a cdna-aflp as a differential display method. a pegfp-tgif2lx constr...

background and objective: breast cancer is the commonest cancer of indian women. estrogen and progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

Primary fallopian tube carcinoma is a rare tumor that histologically and clinically resembles epithelial ovarian cancer. Here we introduce a case of tubal carcinoma in a postmenopausal woman. The diagnosis of primary fallopian tube carcinoma is rarely considered preoperatively and is usually first appreciated by the pathologist. Because of low frequency of tubal carcinoma, there are few systemi...

background: a soluble form of her-2/neu extracellular domain (sher-2) is reported to be released in the sera of metastatic breast cancer patients. objective: to measure the level of sher-2 in sera of 115 breast cancer patients. methods: serial samples of 27 patients with metastasis, 18 non-metastatic patients, 15 patients in stage 0/i and 14 patients with accompanying benign breast disease were...

Objective(s) P53 is an important tumor suppressor, which is mutated in later stages of many cancers and leads to resistance to chemotherapy. The aim of this study was to reveal mutations of TP53 in colorectal cancer in Kerman province. Materials and Methods A total of Forty-three colon cancer specimens as paraffin block or fresh tissues, which passed stage IIIA, were selected. Three exons 5,...

Background: To explore a possible rela!onship among blood groups and the prognosis of breast cancer, this case- control study was carried out in Arak city, Arak province, Iran. Materials and Methods: One hundred and thirty four pa!ents with breast cancer were inves!gated. ABO blood groups were obtained from medical records. Mul!variate analyses were performed, including size of tumor, axilla...