The current classification of lymphoid neoplasms is based on clinical information, morphology, immunophenotype, and molecular genetic characteristics. Despite technical and scientific progress, some aggressive B-cell lymphomas with features overlapping between two different types of lymphomas remain difficult to classify. The updated 2008 World Health Organization (WHO) classification of Tumour...

Breast is an uncommon site of extra nodal lymphoma accounting for 2.2% all lymphomas. B cell lymphomas are more common than T types. The most subtype Diffuse Large Cell Lymphoma. very challenging to diagnose as it has nonspecific clinical and radiological features. We report a rare case primary in 20-year-old female. It was misdiagnosed abscess on ultrasound suppurative mastitis fine needle asp...

Marginal zone lymphomas of all types (nodal, splenic, and extranodal mucosa-associated lymphoid tissue [MALT]) may show plasmacytic differentiation. Distinguishing marginal zone lymphomas from other small B-cell lymphomas with plasmacytic differentiation, especially lymphoplasmacytic lymphoma, or from plasma cell neoplasms may be challenging. Marginal zone lymphomas with plasmacytic differentia...

The shape of alpha-naphthyl acetate esterase (ANAE)-positive cells (other than T lymphocytes) has been measured in 40 lymph nodes. The specimens comprised 15 high-grade lymphomas, 15 low-grade lymphomas and 10 reactive lymph nodes. The parameter used for the measurement of shape was form factor (FF), which is readily calculated by the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analy...

Granzyme M (GM) is a novel serine protease whose expression is highly restricted to natural killer (NK) cells, CD3 CD56 T cells, and T cells. Using a GM-specific monoclonal antibody, we analyzed the expression of GM in 214 mature T-cell and NK-cell lymphomas. GM was preferentially expressed in nasal NK/T-cell lymphomas (100%), T-cell lymphomas (100%), and intestinal T-cell lymphomas (85%). In c...

Cutaneous lymphomas represent a heterogeneous group of malignant lymphoid diseases with particular tropism for the skin. Prognosis and treatment depend on the type of lymphoma, thus precise diagnosis and classification are of paramount importance. Classification of cutaneous lymphomas relies on a synthesis of all available information, including clinical history and presentation, histopathology...

Hodgkin’s lymphomas without extrathoracic involvement or mediastinal adenopathy to determine the clinical, imaging, and endoscopic features of this condition in a homogeneous series. In low-grade (LG) lymphomas, symptoms were cough, dyspnea, chest pain, hemoptysis. Imaging features consisted of localized alveolar opacities, infiltrative diffuse opacities, atelectasis, and pleural effusions. Inf...

To better understand the role of the BCL-3 locus at chromosome 17q22 in the pathogenesis and progression of leukemias and lymphomas, we examined its genomic configuration in 264 B-cell malignancies and its expression in a smaller subset. Cases studied included 39 chronic lymphocytic leukemias, 58 low-grade follicular lymphomas, 20 mantle cell lymphomas, 30 small noncleaved cell lymphomas, 25 ac...

noonan syndrome is an autosomal dominant disorder that is typically evident at birth. in many affected individuals, this syn­drome is associated with cardiac defects and a distinctive facial appearance. the high frequency of cardiac disorder, oph­thalmic, growth and orthopedic signs, associated with noonan syndrome emphasizes the need for early diagnosis. this re­port aimed to present a 19 year...

The management of impacted canines is a complex task and requires lot time to guide them into the arch. In recent years use Kilroy spring has become very popular usually involves heavy main archwire an auxiliary wire canine. this case, modified version was fabricated on archwire, thereby reducing need for second allowing easy guidance canine its normal position