Sir, We thank Drs Bocca Vieira de Rezende Pinto and Sgobbi de Souza for their interest in our recent overview paper on a cohort of patients with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL), caused by DARS2 mutations (Van Berge et al., 2014). Their letter provides us with the opportunity to make specific points clearer. The authors give a summary o...

Except for honey as food, and silk for clothing and pollination of plants, people give little thought to the benefits of insects in their lives. This overview briefly describes significant recent advances in developing insect natural products as potential new medicinal drugs. This is an exciting and rapidly expanding new field since insects are hugely variable and have utilised an enormous rang...

LEAVITr, F. I. Drug-induced modifications in sexual behavior and open field locomotion of male rats. PHYSIOL. BEHAV. 4 (5) 677-683, 1969.---Several drugs were selected for sexual and open field behavioral testing, according to the following criteria: they are known synergists or antagonists of presumptive neurotransmitters; they modify behaviors thought to be related to sexual behavior; or they...