نتایج جستجو برای: capecitabine
تعداد نتایج: 4646 فیلتر نتایج به سال:
Colon cancer (CRC) is one of the most common types in world. In this study, effects Tarantula cubensis alcoholic extract (TCAE) and Capecitabine CRC were investigated. Wistar albino rats divided into eight groups with 12 animals each group: untreated healthy groups, treated TCAE or Capecitabine, both Capecitabine. Azoxymethane was used all groups. administered to relevant starting 15th week. Al...
BACKGROUND We present a retrospective analysis of metronomic capecitabine in metastatic gastroenteropancreatic neuroendrocrine tumors (GEP-NETs). A review of the literature is also presented. METHODS From January 2007 to December 2013, ten patients with metastatic GEP-NETs (four pancreatic and six ileal) who progressed after treatment with somatostatin analogs and other cytotoxic agents recei...
OBJECTIVE The aim of this paper was to compare the efficacy and safety of S-1-based and capecitabine-based preoperative chemoradiotherapy regimens in patients with locally advanced rectal cancer through a retrospective matched-pair analysis. MATERIALS AND METHODS Between Jan 2010 and Mar 2014, 24 patients with locally advanced rectal cancer who received preoperative radiotherapy concurrently ...
Background: This study sought to test the effectiveness of EVOSKIN®Palm and sole moisturizing cream (PSMC) in preventing treating hand-foot syndrome (HFS) during capecitabine chemotherapy.
3552 Background: Capecitabine has the potential to replace 5-FU as standard agent in combination with radiotherapy in rectal cancer. Cetuximab is a monoclonal antibody directed against the epidermal growth factor receptor. Both agents are active in the treatment of colorectal cancer and have demonstrated radiosensitising properties. The aim of this study was to assess the feasibility of combini...
In RCT both tegafur + calcium folinate and capecitabine had a statistically signi cant advantage over 5- uorouracil + calcium folinate: the full and partial objective tumor response was achieved in more patients (table 1). There was no statistically signi cant difference between oral tegafur, both in monotherapy or in combination with calcium folinate, and capecitabine for advanced CRC treat...
We have evaluated the antitumor activity of XELOX (a combination therapy of capecitabine (Xeloda) and oxaliplatin) in human colorectal and gastric cancer xenograft models. In human colorectal cancer model CXF280, antitumor activity of the combination at two-thirds of the maximum tolerated dose (MTD) was superior to that of each monotherapy at MTD. Furthermore, in human colorectal cancer model C...
5-Fluorouracil has been a mainstay in the treatment of colorectal cancer for nearly five decades; however, the use of oral formulations of the medication has been gaining increasing traction since capecitabine was approved for use in adjuvant settings by the US Food and Drug Administration in 2005. The use of capecitabine has since spread to a number of off-label indications, including the trea...
Docetaxel and capecitabine are being prescribed for the treatment of breast cancer. In this study, we tried to identify the optimal administration schedule in combination therapy with these anticancer drugs in human cancer xenograft models. Capecitabine was given p.o. daily for 2 weeks (days 1-14), whereas docetaxel was given i.v. on day 1, day 8, or day 15 in a 3-week regimen to the mice beari...
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