The endothelial glycocalyx has been identified as a barrier to transvascular exchange of fluid, macromolecules, and leukocyte-endothelium [endothelial cell (EC)] adhesion during the inflammatory process. Shedding of glycans and structural changes of the glycocalyx have been shown to occur in response to several agonists. To elucidate the effects of glycan shedding on microvascular hemodynamics ...

Vital organs maintain dense microvasculature to sustain the proper function of their cells. For tissue- engineered organs to function properly, artificial capillary networks must be developed. We have microfabricated capillary networks with a biodegradable and biocompatible elastomer, poly(glycerol sebacate) (PGS). We etched capillary patterns onto silicon wafers by standard micro-electromechan...

Subsurface two-phase flow in porous media often takes place in reservoirs with a high ratio between the associated lateral and vertical extent and the lateral and vertical flow time scales. This allows for a two-scale approach with effective quantities for two-dimensional horizontal flow equations obtained from reconstructed hydrostatic vertical pressure and saturation distributions. Here, we d...

of a Dissertation Submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy BOSTON UNIVERSITY GRADUATE SCHOOL By GEORGE PEARMAN FULTON, JR. S.B., Boston University, 1936 A.M., Boston University, 1938