Ferry services are transport systems whose regular routes link areas separated by water bodies. Sometimes ferries the only connection between an island and mainland. In Baltic Sea, such situations not rare. A typical example is of Saaremaa. Ferries backbone cargo passenger traffic in Sea region. This article aims to describe spatial structure ferry Sea. To this end, a statistical database on 10...

The constitutive active/androstane receptor (CAR) plays an important role as a coordinate transcription factor in the regulation of various hepatic metabolic pathways for chemicals such as drugs, glucose, fatty acids, bilirubin, and bile acids. Currently, it is known that in its inactive state, CAR is retained in the cytoplasm in a protein complex with HSP90 and the tetratricopeptide repeat pro...

Carvone is one of the naturally occurring monoterpenes, the largest class of secondary metabolites in plants, and exists in two enantiomers, R-carvone (R-car) and S-car. The objective of this study was to investigate the antimicrobial activity of R-car and S-car with gentamicin (GET) against methicillin-resistant Staphylococcus aureus (MRSA). MRSA is a major human pathogen that causes serious p...

The expression of coxsackievirus and adenovirus receptor (CAR) was dominant in the brains and hearts of mice until the newborn phase. There is no detailed information concerning the relation between the expression of CAR and development of hearts. It is also uncertain whether CAR is able to be induced in adult hearts after cardiac injury. We demonstrated that CAR was abundant in the hearts of n...

Car body lightening and crashworthiness are two important objectives of car design. Due to their excellent performance, composite materials are extensively used in the car industries. In addition, reducing the weight of vehicle is effective in decreasing the fuel consumption. Hat shape energy absorber is used in car’s doors for side impact protection. The aim of these numerical models and expe...

The chimeric antigen receptor-modified immune effector cell (CAR-T and CAR-NK) therapies are newly developed adoptive treatments of cancers. However, their therapeutic efficacy against solid tumors is limited. Combining CAR-T or CAR-NK cells with chemotherapeutic drugs to treat solid tumor may be a promising strategy. We developed an epidermal growth factor- (EGFR-) specific third-generation CA...

introduction foreign body insertion is a common and important cause of pre-pubertal vaginal bleeding. case presentation we present a three-year-old girl who referred to our clinic with abnormal vaginal bleeding without any other symptoms. the primary assessment revealed a radio-opaque round solid mass in the pelvic cavity. following vaginoscopy, the button battery was finally removed under gene...

conclusions the clinicians should always think of foreign bodies in the vagina in cases of chronic, antibiotic resistant vaginal discharge and lower abdominal pain especially in young girls. introduction foreign body in the vagina is a common cause of vaginal discharge, which may be either purulent or hemorrhagic. case presentation this problem may produce symptoms or be asymptomatic for long p...