Osteogenesis imperfecta (OI) is a heritable systemic disorder of the connective tissue. Dentinogenesis imperfecta (DI), which is sometimes an accompanying symptom of OI, belongs to a group of genetically conditioned dentin dysplasias and is characterized clinically by an opalescent amber appearance of the dentin. Although the teeth of DI cases wear more easily and excessively compared to normal...

background and aims. the aim was to evaluate the effect of casein phosphopeptide–amorphous calcium phosphate (cpp-acp) on microtensile bond strength (µtbs) to carious affected dentin (cad) using etch-and-rinse and self-etch adhesive systems. materials and methods. the occlusal surface of 32 human molars with moderate occlusal caries was removed. infected dentin was removed until reaching cad an...

Pre-eruptive intracoronal resorption is a lesion often located within the dentin, adjacent to the dentin-enamel junction, in the occlusal aspect of the crown. As the lesions resemble caries, they are often referred as "pre-eruptive caries." The purpose of this case report was to describe the diagnosis and treatment of a permanent molar with pre-eruptive intracoronal resorption and to elaborate ...

Caries is a tooth surface disease characterized by demineralization caused acids produced bacteria during the metabolism of sugar food. Molars are primary teeth that most prone to caries. One causes caries poor dental and oral hygiene. Preschoolers have lower awareness adherence hygiene, increasing risk The objective this study was examine description molars as well effect health education on h...

Streptococcus mutans is a key bacterium in dental caries, one of the most prevalent chronic infectious diseases. Conventional treatment fails to specifically target pathogenic bacteria, while tending eradicate commensal bacteria. Thus, caries remains common and challenging Phage therapy, which involves use bacterial viruses as anti-bacterial agents, has been gaining interest worldwide. Neverthe...

It is generally accepted that three conditions are essential in the oral cavity for dental caries to occur: a suitable microbe, a substrate for the microbe, and a susceptible tooth. Susceptibility or resistance to dental caries is usually thought of in terms of structure, which is determined, for the most part, during calcification. However, it is also plausible that susceptibility to dental ca...

Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand, Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Division of Conservative Dentistry, GKT Dental Institute, London, United Kingdom, and Center of Excellence Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone, Tokyo M...

During primary dentin formation, differentiating primary odontoblasts secrete an organic matrix, consisting principally of type I collagen and non-collagenous proteins, that is capable of mineralizing at its distal front. In contrast to ameloblasts that form enamel and undergo programmed cell death, primary odontoblasts remain metabolically active in a functional tooth. When dentin is exposed t...

To investigate the effectiveness of topical fluorides in preventing fissure caries, we conducted a randomized controlled trial with parallel groups. In total, 501 children (1,539 molars, 3,078 sites), mean age 9.1 years, who had at least one sound permanent first molar with deep fissures or fissures with signs of early caries were recruited. They were randomly allocated among four groups: (1) r...