BACKGROUND Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum beta-carotene, alpha-carotene, vitamins A and E) would be at a higher risk of accelerated decline in forced expiratory volume in 1 second (FEV1) as their lungs would be less protected against oxidative ...

BACKGROUND Beta-Carotene has been reported to produce regressions in patients with oral leukoplakia, a premalignant lesion. However, previous studies have all been of short duration, with clinical response as the end point. OBJECTIVE To evaluate the duration of response and the need for maintenance therapy in subjects who respond to beta-carotene. METHODS In this multicenter, double-blind, ...

The flowers of twenty-three cultivars of Dendranthema grandiflorum Ramat. were investigated to determine anthocyanin and carotenoid levels and to confirm the effects of the pigments on the flower colors using high-performance liquid chromatography (HPLC) and electrospray ionization-mass spectrometry (ESI-MS). The cultivars contained the anthocyanins cyanidin 3-glucoside (C3g) and cyanidin 3-(3"...

Two primary prevention trials unexpectedly showed adverse effects of supplemental beta-carotene on lung cancer incidence in cigarette smokers. To elucidate the molecular mechanisms that might underlie these effects, we studied the immunohistochemical expression of cytochrome P450 1A1, 1A2, and 2E1, retinoic acid receptor beta, activated protein-1 elements, cyclin D1, and Ki67 in lung tumors and...

Beta-carotene is converted in the body to vitamin A, a powerful antioxidant that plays an essential role maintaining healthy eyes, skin, and neurological function. other carotenoids have activities are valued for their ability prevent chronic disease. β-carotene found yellow, orange, red, green fruits. The purpose of this study was determine Jongi. Jongi (Dillenia Serrata Thunb.) endemic fruit ...

closely controlled. The multi-infarct group had an -intermediate mean plasma carotene concentration and showed no significant correlation between plasma carotene and plasma vitamin A concentrations (Spearman coefficient 0 32). These findings very probably result from including patients who also have Alzheimer's disease in the multi-infarct group.5 The cause of carotenaemia in Alzheimer's diseas...

Six varieties of mangoes (Amelia, Brooks, Kent, Keitt, Lippens, Springfield)harvested from different pedological areas of the western region of Burkina Faso (Bobo-Dioulasso, Orodara, Banfora) were analyzed by high performance liquid chromatography in order to determine the β-carotene content. The study revealed a variability in β-carotene content between different varieties and regions. The Ame...

Initial findings from two major clinical trials, the BetaCarotene and Retinol Efficacy Trial (CARET) in the United States (7) and the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC Study) in Finland (2), unexpectedly showed that supplemental p-carotene alone or in combination with retinol appeared to increase the risk of lung cancer, particularly in current smokers. CARET also re...

Orange Fleshed Sweet Potatoes (OFSPs) is an excellent nutrition sensitive function food. It contains dense amount of carotene and also rich in proximate nutrients. A wide number cultivars OFSPs has been developed worldwide, particularly sub-Saharan Africa Asia. In Bangladesh, sixteen have developed. Carotene content the surpasses all plant food carotene. good energy yielding The could, therefor...

BACKGROUND Orange-fleshed sweet potato is an efficacious source of vitamin A. Substituting wheat flour with orange-fleshed sweet potato in processed products could reduce foreign exchange outlays, create new markets for producers, and result in increased vitamin A consumption among consumers provided there is adequate retention of beta-carotene during processing. OBJECTIVE To explore whether ...