Whether endothelial dysfunction in essential hypertension is a cause or a consequence of structural vessel wall alterations is not known. The purpose of the present study was to compare flow-mediated vasodilation and mechanical vessel wall properties of large arteries between never treated mild essential hypertensive patients with normal intima-media thickness (IMT) and those exhibiting intima-...

Non Invasive assessment techniques of atherosclerosis include Pulse-wave velocity at the brachial artery, Intima media thickness (IMT) in the carotid artery, Multi (64)-slice computed tomography (MSCT) for imaging of coronary lesions, Arterial pulse wave form analysis, Ankle Brachial Index (ABI) and Computed Tomography for coronary calcium. The potentially applicable screening tools have to be ...

OBJECTIVE To better understand the mechanism of stroke during cardiopulmonary bypass, it is necessary to obtain information on the location of turbulence, wall pressure, and flow distribution within the aortic arch. METHODS Blood flow was numerically simulated using the finite element method in the following representative case: a curved arterial cannula was inserted into the anterior wall of...

Nine cases of carotid body tumor chemiodectomas in seven Patients are presented and diagnostic and therapeutic problems discussed Similar to other reports, many cases undergo operative exploration without correct preoper.ativ.e diagnosis or ability of the surgeon to handle such lesions. The most important factor for correct diagndsis is including carotid body in differential diagnosis of latera...

BACKGROUND Although much has been written in recent years about the relation between alcohol and atherosclerotic disease, controversy exists as to whether and how alcohol exerts an effect on atherosclerosis in different sites. METHODS AND RESULTS We tested the hypothesis that alcohol consumption is associated inversely with carotid atherosclerosis in a population sample of 45- to 64-year-old ...

Background. Although much has been written in recent years about the relation between alcohol and atherosclerotic disease, controversy exists as to whether and how alcohol exerts an effect on atherosclerosis in different sites. Methods and Results. We tested the hypothesis that alcohol consumption is associated inversely with carotid atherosclerosis in a population sample of 45to 64-year-old me...

Background. Although much has been written in recent years about the relation between alcohol and atherosclerotic disease, controversy exists as to whether and how alcohol exerts an effect on atherosclerosis in different sites. Methods and Results. We tested the hypothesis that alcohol consumption is associated inversely with carotid atherosclerosis in a population sample of 45to 64-year-old me...

Based on the interpretation of several experimental investigations, the study of carotid hemodynamics in hypertension has long been restricted to the pathophysiologic problems related to high-pressure baroreceptors.Indeed, the arterial wall of the carotid bifurcation contains receptors that play a large part in the regulation of blood pressure and that are considered to be reset to higher press...

Fibromuscular dysplasia (FMD) is a noninflammatory, nonatherosclerotic disorder that cause arterials steno- sis, occlusion, aneurysm, dissection, and artery tortuosity. The etiology of FMD remains unknown. most frequently involved arteries are the renal, internal carotid, vertebral visceral. Among adults, more common in females. Most symptoms renovascular hypertension, headache, pulsatile tinni...

OBJECTIVES We compared in vivo 3.0-T magnetic resonance (MR) images of the carotid artery wall in piglets to intima-media thickness measurements of similar carotid segments by B-mode ultrasound (US) and histology to define the corresponding anatomical tissue characteristics and accuracy of carotid MR images. BACKGROUND Carotid MR is increasingly used for the assessment of cardiovascular risk ...