AIM To analyze the clinical and pathological parameters and expression of the neural cell adhesion molecule (CD56) in patients with biliary atresia (BA). METHODS Established clinical laboratory markers of hepatic function, including enzyme activity, protein synthesis, and bilirubin metabolism, were evaluated in patients with BA and compared with those in patients with choledochal cysts and ne...

BACKGROUND Increased peripheral blood natural killer (NK) cell activity has been associated with unexplained reproductive failure including recurrent (three or more) miscarriages (RM). Studies have reported abnormalities in both numbers (absolute and proportion) and activation. This study assessed numerous NK cell parameters to determine which (if any) are altered in women with RM compared with...

introduction: natural killer (nk) cells, of which cd56 is a specific marker, play an important role in host defense against tumors. cancer stem cells, of which aldehyde dehydrogenase isoform 1 (aldh1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. we aimed to evaluate the expression of aldh1 and cd56 in common salivary g...

Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...

The aim: to find the optimal combination of immunohistochemical markers for differential diagnosis and prognosis small cell lung cancer in biopsy samples.
 Materials methods. tumor specimens were divided into 3 groups: 1) 25 samples before treatment; 2) procured from autopsies patients, who underwent chemotherapy; 3) 15 other tumors histologically similar SCLC. All formalin fixed paraffin ...

The Notch signaling pathway plays a substantial role in human NK cell development. However, the role of Notch on killer Ig–like receptor (KIR) upregulation and acquisition of effector function has not been explored. To evaluate how Notch influences terminal differentiation , cord blood–derived NK cells or sorted peripheral blood NK cells were cultured with IL-15 for 7 d with inhibitory or activ...

Published articles has been reprinted with the permission of the copyright holder. iii To my family because you are always there " An experiment is a question which science poses to Nature, and a measurement is the recording of Nature's answer. " Abstract v ABSTRACT The atherosclerotic process is considered to be driven by an imbalance between pro-and anti-inflammatory actions. Still, the infla...

Introduction: Salivary gland cancers impose a huge part in oral and maxillofacial pathologies. Mucoepidermoid (MEC) adenoid cystic carcinomas (ACC) are salivary malignancies, where being the most common cancer. CD44, is family of transmembrane non-kinase cell surface glycoproteins, that was broadly used as marker for cancer stem cells (CSCs) various malignancies. CD44 found to be overexpressed ...