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congenital dislocation of the knee (cdk) is a rare disorder. we report the case of a 7-year-old girl with bilateral knee stiffness, marked anterior bowing of both legs, and inability to walk without aid. radiologic investigation revealed bilateral knee joint dislocation accompanied by severe anterior bowing of both tibia proximally and posterior bowing of both femur distally, demonstrating a co...

Cyclin-dependent kinases (CDKs) function as central regulators of both the cell cycle and transcription. CDK activation depends on phosphorylation by a CDK-activating kinase (CAK). Different CAKs have been identified in budding yeast, fission yeast, and metazoans. All known CAKs belong to the extended CDK family. The sole budding yeast CAK, CAK1, and one of the two CAKs in fission yeast, csk1, ...

Although the Chemistry Development Kit (CDK) [1, 2] and Octet [3, 4] are similar in several respects, they also differ in important ways. Because of these differences, software based on one platform is incompatible with software based on the other. CDKTools is designed to solve this problem by enabling both Octet and CDK to be used interchangeably [5]. This article describes the most important ...