background: we had previously identified the genes involved in squamous cell carcinoma of the head and neck using differential display and dna microarray techniques. we also reported the first analytical study on a novel human gene called loc92912, which was identified by differential display as a gene up-regulated in such carcinomas. loc92912, which is a putative member of the e2 ubiquitin con...

The paper reviews various topics in shape analysis. In particular, matching configurations using regression is emphasized. Connections with general shape spaces and shape distances are discussed. Kendall’s shape space and the affine shape space are considered in particular detail. Matching two configurations and the extension to generalized matching are illustrated with applications in electrop...

Differences between image processing and other disciplines in the definition and the role of shape are explored. Diverse approaches to quantifying shape are reviewed. Attention is drawn to the need for close coupling between image acquisition and shape analysis. An example of the effect of the means of observation on dynamic shape extraction is drawn from linguistics. Current instrumentation fo...

Motions of virtual characters in movies or video games are typically generated by recording actors using motion capturing methods. Animations generated this way often need postprocessing, such as improving the periodicity of cyclic animations or generating entirely new motions by interpolation of existing ones. Furthermore, search and classification of recorded motions becomes more and more imp...

Local scale variations within the same species are common in nature. The shape matching puzzle poses fascinating questions, like how should we measure the discrepancy between a small dog with large ears and a large one with small ears? are there similar geometric structures that are common to an elephant and a giraffe? what is the morphometric similarity between a blue whale and a dolphin? Exis...

Single cell morphogenesis results from a balance of forces involving internal pressure (also called turgor pressure in plants and fungi) and the plastic and dynamic outer shell of the cell. Dominated by the cell wall in plants and fungi, mechanical properties of the outer shell of animal cells arise from the cell cortex, which is mostly composed of the plasma membrane (and membrane proteins) an...

Bacteria have remarkably robust cell shape control mechanisms. For example, cell diameter only varies by a few percent across a population. MreB is necessary for establishment and maintenance of rod shape although the mechanism of shape control remains unknown. We perturbed MreB in two complimentary ways to produce steady-state cell diameters over a wide range, from 790±30 nm to 1700±20 nm. To ...

Previous Work: Several prior algorithms attempt to provide a deformation-invariant distance measure. Tangent distance [2] uses a planar approximation to a local image manifold, allowing small spatial transformations to be modeled in pixel space. Because of the planar approximation, tangent distance does not work well for large deformations. The “shape context” method [1] is good at obtaining de...

Statistical shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes and thus potentially discriminate between healthy and pathological structures. This paper describes a combined boundary and medial shape analysis based on two different shape descriptions applied to a study of the hippocampus shape abnormaliti...

The topography of a biomaterial regulates cellular interactions and determine stem cell fate. A complete understanding of how topographical properties affect cell behavior will allow the rational design of material surfaces that elicit specified biological functions once placed in the body. To this end, we fabricate substrates with aligned or randomly organized fibrous nanostructured topographi...