AIM This study aims to create a predictive model for the assessment of the individual risk of developing cerebral palsy in a large cohort of selected high-risk infants. PATIENTS AND METHODS 1099 NICU-admitted high-risk infants were assessed up to the corrected age of at least 12 months. CP was categorized relative to subtype, distribution and severity. Several perinatal characteristics (gende...

objectives: hypertonicity is a major problem in children with cerebral palsy that has not been explained effectively to address clinical decision making. therefore, this article aims to provide a theoretical framework about hypertonicity for clinicians, rehabilitation and medical practitioners to be used in their practice. methods: literature was reviewed to examine the new perspectives towards...

There is a need for appropriate classification to describe gross motor function status in a child with cerebral palsy (CP). It was hypothesised that: greater the number of limbs involved, higher would be the Gross Motor Function Classification System (GMFCS) level; and, there would be spectrum of GMFCS level for each of the topographical types of the cerebral palsy. A cross-sectional study of 1...

Management of children with cerebral palsy (CP) is the focus of considerable resources in many countries, so that evaluation of the efficacy for new and established treatments is imperative. Botulinum toxin type A (BTX-A) is a relatively new method of spasticity management in children with cerebral palsy. It has been the focus of extensive research since its application to cerebral palsy 10 yea...

The paper describes a novel system and a physical therapy method for rehabilitating the affected limbs of infants and children diagnosed with hemiplegic cerebral palsy (CP). Currently, the most effective procedure for the treatment of cerebral palsy is constraint-induced movement therapy (CIMT), which includes limiting the movement of the unaffected arm to encourage the use of the affected arm....

Cerebral palsy (CP) is a severe type of brain disease affecting movement and posture. Although CP has strong genetic and environmental components, considerable differences in the methylome between monozygotic (MZ) twins discordant for CP implicates epigenetic contributors as well. In order to determine the differences in methylation in patients with CP without interference of the interindividua...

AIM To assess development of reaching and head stability in infants at very high risk (VHR-infants) of cerebral palsy (CP) who did and did not develop CP. METHOD This explorative longitudinal study assessed the kinematics of reaching and head sway in sitting in 37 VHR-infants (18 CP) one to four times between 4.7 months and 22.6 months corrected age. Developmental trajectories were calculated...

White matter lesions are often seen in children with spastic cerebral palsy (CP). Evidence points to specific impairment of attentional, visuospatial, and executive functions; although both attention and executive functions are relatively unexplored in spastic CP. The few recent studies on language functions in mild or moderate CP point to well-functioning language. The presence of specific cog...

Isometric voluntary force production and relaxation capacity of the quadriceps femoris (QF) muscle was compared between 12 children with spastic diplegic cerebral palsy (CP) and healthy controls, age 10-11 years. Children with CP had less (p < .05) maximal voluntary-contraction force, voluntary activation, and rate of force development than controls. Visual reaction to contraction did not diffe...

Cerebral palsy is a disorder of posture and movement.[15] These children grow poorly throughout their lives.[2,16,17] They have significantly lower mean height,[18–20] weight,[7,18–20] skinfold thickness,[7,19] and mid upper arm circumference (MUAC)[7,18] as compared to general population. Communitybased cross-sectional surveys in Philippines,[21] Nigeria,[22] Bangladesh,[15] and India[19] have...