Point count stereology is a useful tool in obtaining volumetric measures of objects in three-dimensional (3D) images when the segmentation of objects is not feasible. Presently, fixed-grid 3D stereology is being used where a 3D parallelepiped grid is randomly placed for sampling the image space in order to generate test points. Although this is a popular technique, the use of a fixed grid intro...

The condition of hydrocephalus (HCP) and its secondary sequelae have been well documented. Previous reports have documented the impact of an enlarging ventricular system on the developing brain and neuropsychological consequences in HCP children. Furthermore, most children with shunted HCP have been reported to demonstrate poorer non-verbal intelligence quotient (IQ) scores relative to verbal I...

The evidence that new neuron addition takes place in the mammalian brain throughout adult life has dramatically altered our perspective of the potential for plasticity in the adult CNS. Although several recent reports suggest a latent neurogenic capacity in multiple brain regions, the two major neurogenic niches that retain the ability to generate substantial numbers of new neurons in adult lif...

Cyclophosphamide, a model teratogen, has been used to produce hydrocephalus experimentally by various researchers [1–4]. Although the precise mechanism of cyclophosphamide induced hydrocephalus remains elusive, hypertrophy of choroid plexus was considered as the primary cause [1,4]. Singh et al [4] observed agenesis or stenosis of the aqueduct as an associated reason. The present work has been ...

A diffuse, chronic, superficial neocortical degeneration that resulted in atrophy was detected in five 1 to 2-year-old-dogs. Presenting neurologic signs included ataxia, dysphagia, blindness, and mentation changes. Magnetic resonance imaging on brains from 2 dogs demonstrated severe bilateral cerebrocortical atrophy and enlarged lateral and third ventricles. Grossly, multifocal, bilaterally sym...

Background: Cerebral edema (CE) and intracranial hypertension (IHT) are complications of numerous neurological pathologies. However, the study CE noninvasive methods to predict IHT remains rudimentary. This aims identify in traumatic brain injury (TBI) patients relationship between volume lateral ventricles parameters pressure waveform (nICPW). Methods: is an analytical, descriptive, cross-sect...

Sixty patients with severe head injury who did not have an acute intracranial haematoma on CAT scanning are reviewed. The scans are correlated with the level of consciousness at the time of scanning and with the outcome six months after injury. The initial scan was interpreted as being normal in 38% of the cases. In the remainder the most common abnormalities were small ventricles and areas of ...

Computed tomography of the brain was performed in thirty schizophrenic patients in the age group of 19-45 years and thirty controls matched for age and sex The size of lateral ventricles, the width of the third ventricle and the sylvian fissure were measured in the CT scans. On group comparison, we found that the size of lateral ventricles expressed as ventricular brain ratio, and the width of ...

The main objective of this retrospective review of clinical and cerebrospinal fluid (CSF) data from 41 patients with intracranial tumors diagnosed between 1975 and 1989, is to report the role that the finding of neoplastic cells in CSF plays, specially when cerebral CT-scanning and MRI were not currently done. Another objective is to study the CSF proteic abnormalities in cerebral tumors. CSF c...

The CT scans of 74 patients presenting with late-onset epilepsy not due to cerebral tumour were compared with those of an age and sex-matched control group for evidence of cerebral vascular disease. Changes in the scan indicative of cerebral atrophy (enlarged ventricles and cortical sulci) were seen in similar numbers in both patients and controls. However, the scans revealed a highly significa...