Wheat germ agglutinin (WGA) is a lectin that specifically binds cell surface glycoproteins and disrupts nuclear pore complex function through its interaction with POM121. Our data indicate WGA induces paraptosis-like cell death without caspase activation. We observed the main features of paraptosis, including cytoplasmic vacuolation, endoplasmic reticulum dilation and increased ER stress, and t...

Achalasia is a primary esophageal motility disorder that involves failure of the lower sphincter to relax in response swallowing. Specifically, becomes hypertensive, and there an absence peristalsis esophagus. The pathophysiology thought be due loss inhibitory nerve function from autoimmune attack targets myenteric nerves. As result, these abnormalities lead functional obstruction at gastroesop...

critical pulmonary valve stenosis (cpvs) and atrial septal defect (asd) is an uncommon form of congenital heart disease. concurrent transcatheter pulmonary valvuplasty and closure of secundum atrial septal defect appears to be an interesting alternative to surgical correction. we present the simultaneous balloon valvuloplasty of critical pulmonary stenosis (ps) with supra systemic right ventric...

OBJECTIVE To determine whether sonographic measurement of cervical length in twin pregnancies presenting with threatened preterm labor helps distinguish between true and false labor. METHODS In 87 women with twin pregnancies presenting with regular and painful uterine contractions at 24-36 (median, 30) weeks of gestation, cervical length was measured by transvaginal ultrasound. Women presenti...

Cervical laceration has been identified as a known cause of postpartum hemorrhage. A review of existing literature obtains little information on the incidence and risk factors for cervical laceration after vaginal delivery (1). In the Iranian Traditional Medicine, all types of vaginal, cervical and uterine lacerations named as a common term of uterine fissure or "sheghaghe rahem". In this field...

background: achalasia is the most recognized esophageal motor disorder with an unknown etiology. symptoms rather than physical findings are hallmarks of the disease. modalilies for treatment include pharmacologic, botulinum toxin injection, pneumatic dilation and surgery. materials and methods: to review the diagnostic and therapeutic options currently available for achalasia. a medline search ...