Recently updated cervical screening guidelines have proposed a 5-year screening interval for women aged 30 years and older with "double-negative" Papanicolaou (Pap) and high-risk human papillomavirus (hrHPV) results (DNR); however, published US follow-up data on women with DNR tested with US Food and Drug Administration (FDA) - approved HPV testing are limited to studies from Kaiser Permanente ...

Cytomegalovirus and Chlamydia trachomatis are prevalent sexually transmissible pathogens. They produce persistent infections of the cervix and have been associated with cervical neoplasia. Cytomegalovirus has also been shown to induce transformation of cells in culture. Because of the high prevalence of genital infections with these pathogens and evidence that they may have oncogenic effects on...

A 44‐year‐old woman was admitted to our hospital with a 10‐day history of ache of double upper limbs and numbness on the trunk below the chest and bilateral thighs. Ten days before, she had an onset of ache of double upper limbs without apparent inducement. At the same time, she developed trembling on hands when writing and numbness between the chest and bilateral knees, which were unable to be...

Cytomegalovirus and Chlamydia trachomatis are prevalent sexually transmissible pathogens. They produce persistent infections of the cervix and have been associated with cervical neoplasia. Cytomegalovirus has also been shown to induce transformation of cells in culture. Because of the high prevalence of genital infections with these pathogens and evi dence that they may have oncogenic effects o...

OBJECTIVE To increase awareness of the limitations of high-risk human papillomavirus (hrHPV) laboratory-developed testing (LDT) widely used in US cervical cancer screening. METHODS AND RESULTS A young woman in her 30s was diagnosed and treated for stage 1B1 cervical squamous cell carcinoma in which HPV 16 DNA was detected using polymerase chain reaction testing. Both 1 month before and 42 mon...

AIMS To explore the following in a group of carcinoma cervix patients with chronic periodontitis: The possible association of the Human Cytomegalovirus (HCMV) in chronic periodontitis and carcinoma of the cervix by examining the presence of HCMV (Human Cytomegalovirus) in saliva, Gingival Crevicular Fluid (G.C.F.) and in cervical biopsy samples and by comparing the clinical parameters among the...

PURPOSE The purpose of this study was to analyze the ultrasonographic (USG) findings of Kikuchi cervical lymphadenopathy in pediatric patients. METHODS Between April 2007 and September 2016, 84 children (42 male and 42 female; mean±standard deviation age, 12.9±3.2 years; range, 5 to 18 years) confirmed with Kikuchi disease were enrolled. Clinical findings and USG findings of Kikuchi cervical ...

Background: Cytokines are suggested to play a role in periodontitis. Objective: To determine and compare the levels of Interleukin-1 beta (IL-1β) and Tumor necrosis factor alpha (TNF-α) in gingival crevicular fluid (GCF) samples amongst healthy individuals and  those with chronic periodontitis. Further to compare the GCF cytokine levels in three genotype classes defined by the respective gene p...

OBJECTIVES To demonstrate a rare but potential mechanism of quadriplegia in a patient with fulminant pneumococcal meningitis complicated by severe intracranial hypertension. DESIGN Case report. SETTING Intensive care unit. PATIENT A 21-year-old man who presented with 3 days of headache, combativeness, and fever. INTERVENTION Antibiotics and steroids were initiated after lumbar puncture ...