Neoplasm in the vagina which occurs following treatment of cervical carcinoma could represent a separate primary neoplasm, a “field” response to a common carcinogen, or be due to neoplastic transformation of tissue from previous radiation treatment. Fifty patients with a second neoplasm in the vagina were identified: 17 following total hysterectomy for carcinoma in situ of cervix; 4 following r...

Despite considerable progress in understanding the function of peroxiredoxin (Prx) in cancer, its expression patterns have not been extensively studied in response to cervical carcinogenesis. We evaluated the expression of Prx isoforms in normal tissue, cervical intraepithelial neoplasia (CIN1, CIN2, and CIN3), and cervical cancer. We found strong pattern of increased Prx II and III immunostain...

AIM Cyclins are a family of regulatory proteins that play a key role in controlling the cell cycle. Abnormalities of cell cycle regulators, including cyclins and cyclin dependent kinases, have been reported in various malignant tumors. This study was undertaken to quantitatively detect cyclin B1 and D1 in cervical cancer. METHODS A quantitative real-time reverse transcription polymerase chain...

BACKGROUND Our previous study reported that MEG3 is an important tumor suppressor gene that is inactivated in cervical cancer. However, the diagnostic and prognostic values of MEG3, as well as the molecular mechanism of MEG3 inactivation in cervical cancer, remain unclear. In this study, we aimed to further elucidate the role and potential inactivation mechanism of MEG3 in cervical cancer. ME...

This study aims to investigate the expression and clinical significance of CC chemokine ligand 18 (CCL18) in the serum and tumor tissue of the patients with oral squamous cell carcinoma (OSCC). Enzyme linked immunosorbent assay (ELISA) was used to detect the serum CCL18 contents in 59 patients with OSCC and 17 healthy adults; immunohistochemistry was used to detect the CCL18 expressions in 97 s...

Fat-associated lymphoid clusters (FALCs) are novel tissues that have been reported in the mesenteric and mediastinal fat tissue of mouse human. It plays role progression respiratory intestinal inflammation parasitic infestations. However, their occurrence chicken air sacs adipose has not yet identified. Here we investigated distribution FALCs (cervical, clavicular, thoracic, abdominal) healthy ...

High-risk human papillomavirus types are associated with most of cervical cancer cases. To explore the mechanism by which 16 infections interferes progression and immune evasion acting on T helper 9 cells cytokines. Cervical were obtained from China Center for Type Culture Collection. Cells cultured in Roswell Park Memorial Institute Medium-1640. Through wound healing test transwell analysis, e...

Prematurity affects 11% of the births and is the main cause of infant mortality. On the opposite case, the failure of induction of parturition in the case of delayed spontaneous birth is associated with fetal suffering. Both conditions are associated with precocious and/or delayed cervical ripening. Quantitative and objective information about the temporal evolution of the cervical ripening may...

Bronchogenic cysts are benign congenital malformations derived from the tracheobronchial tree that correspond to non-functioning lung tissue.1,2 The majority of cases are diagnosed in the pediatric population.3 In adults they are fundamentally found in mediastinum and lung parenchyma.3 However, they can sometimes be located in the thoracic wall, abdomen or cervical region4; in the cervical area...

ectopic thyroid tissue results from abnormal embryologic development and migration of the thyroid gland. true malignant transformation in ectopic thyroid tissue is extremely rare and is always diagnosed after surgical excision of the lesion by pathology examinations. there are well-documented cases of ectopic thyroid cancer while primary tumoral lesion occurs in the orthotopic thyroid, but only...