The virus was first isolated in April 1947 from a rhesus macaque monkey placed cage the Ziika Forest of Uganda, near Lake Victoria, by scientists Yellow Fever Research Institute. A second isolation mosquito A. africanus followed at same site January 1948. When developed fever, researchers its serum

Everyday work involves communicating, coordinating and collaborating with others. In many cases employees are situated in geographically distributed offices, and hence lack a general sense of their co-workers’ current activities and availability. At present, many companies invest money in communication systems that enable formal interactions, such as video conferencing. There are however few te...

Highly efficient systems are needed to link perception with action in the context of the highly complex environments in which primates move and interact. Another important component is, nonetheless, needed for action: selection. When one piece of fruit from a branch is being chosen by a monkey, many other pieces are within reach and visible: do the perceptual features of the objects surrounding...

1. The response properties of 354 single neurons in the medial (M), dorsomedial (DM), dorsolateral (DL), and middle temporal (MT) visual areas were studied quantitatively with bar, spot, and random-dot stimuli in chronically implanted owl monkeys with fixed gaze. 2. A directionality index was computed to compare the responses to stimuli in the optimal direction with the responses to the opposin...

We succeeded in cloning the rhesus monkey nociceptin/orphanin FQ peptide (NOP) receptor. The nucleotide sequence and amino acid sequence of the rhesus monkey NOP receptor were 95.9% and 97.8%, respectively, identical to the human NOP receptor. There was no significant difference between the rhesus monkey NOP receptor and the human NOP receptor in the binding affinity of [(125)I] [Thy(14)]nocice...

The effect of P-glycoprotein (Pgp) and/or CYP3A on the disposition of xenobiotics has been extensively investigated and is often of interest during drug discovery lead optimization. We have previously described a monkey pharmacokinetic screen to rapidly estimate absorption and first-pass extraction. In the present work, this monkey screen has been expanded to include an assessment of Pgp/CYP3A ...

Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains challenging due to the lack of a complete protein sequence database and effective strategy. To investigate the most effective and high-throughput pr...

Peripheral blood mononuclear cells (PBMC) from three adult male squirrel monkeys (Saïmiri sciureus) were transformed by human T-cell leukemia/lymphoma virus type I (HTLV-I) by cocultivation with lethally irradiated human MT-2 cells. Three permanent monkey T-cell lines producing HTLV-I were obtained and characterized. Six weeks after inoculation seroconversion was observed in three of three monk...

OBJECTIVE This study is to establish the rhesus monkey model of lymphedema in the upper limbs, and assess the suitability of this model. METHODS An animal model of lymphedema was established by the combined irradiation and surgical techniques in the upper limbs of these rhesus monkeys. Physical examination, high-resolution MR lymphangiography, bioelectrical impedance analysis (BIA), and immun...