This review examines the use of Caco-2 monolayers in the prediction of intestinal drug absorption. First, the different routes of drug transport in Caco-2 monolayers are compared with those seen in vivo. Second, the prediction of drug absorption in vivo from transport experiments in cell monolayers is discussed for different classes of drugs. Finally, the use of Caco-2 monolayers as a reference...

Absorption determined by mass transfer in the liquid is described well with the Graetz-L&&que equation adapted from heat transfer. The influence of a chemical reaction on the mass transfer was simulated with a numerical model and tested on the absorption of CO2 in a hydroxide solution. Absorption determined by mass transfer in the gas phase and the pores of the membrane was also analysed experi...

Stable films containing CdS quantum dots of mean size 3.4 nm embedded in a solid host matrix are prepared using a room temperature chemical route of synthesis. CdS/synthetic glue nanocomposites are characterized using high resolution transmission electron microscopy, infrared spectroscopy, differential scanning calorimetry and thermogravimetric analysis. Significant blue shift from the bulk abs...

Shortwave infrared (SWIR) spectroscopy can be applied directly to analyze the mineral chemistry of raw or geologic materials. It provides diagnostic spectral characteristics of the chemical composition of minerals, information that is invaluable for the identification and quality control of such materials. The present study aims to investigate the potential of SWIR spectroscopy as an alternativ...

1 Chemical transport through human skin can play a significant role in human exposure to toxic 2 chemicals in the workplace, as well as to chemical/biological warfare agents in the battlefield. 3 The viability of transdermal drug delivery also relies on chemical transport processes through the 4 skin. Models of percutaneous absorption are needed for risk-based exposure assessments and drug5 del...