Corneal neovascularization is a serious condition that may arise secondary to chemical burns, ischemia, infection, trauma, and inflammation and represents a major cause of blindness. This study investigated the efficacy of topical application of infliximab [tumor necrosis factor-a (TNF-a) monoclonal antibody] in the treatment of corneal neovascularization in the rabbit model.

A retrospective study was conducted of burn patients admitted to the military hospital in Rabat, Morocco, in the 6-yr period from 2004 to 2009. This is the first multivariate study to be performed in Morocco. The epidemiological data from the 291 patients hospitalized were collected and studied. The type of burn was indicated in 284 of the patients: 94% of the injuries were thermal burns, 4% we...

BACKGROUND Electrical burns account for a significant percentage of fatal accidents. Each year, a number of consumers in Iran suffer from electrical injuries due to technical problems, equipment failures, and the unauthorized use of electricity. The aim of this study was to examine the root causes of accidents that involved electricity in the district served by the Western Tehran Province Elect...

GLACIAL acetic acid, though extensively used in manufacturing processes, is not commonly seen as a cause of chemical burns of the eye. Two cases which have been seen recently are thought to be of sufficient interest to warrant description, there being little reference to such injuries in the literature. In both cases glacial acetic acid was put by mistake into the eye by the patient, instead of...

This article describes the management of chemical burns to the Asian face with resultant full thickness loss to the right side of the face including the eyelid and nose. We detail the techniques used to reconstruct the face which include skin grafting according to the aesthetic units of the face, accurate placement of junction lines, use of a chondrocutaneous graft to reconstruct the alar grove...

Dr Trevor Laird, Managing Director and Founder of Scientific Update LLP, is an expert in organic process R&D and scale-up of chemical processes and has been an editor-in-chief of the American Chemical Society journal Organic Process Research and Development since its launch in 1996. With over 4 decades of involvement with the chemical and pharmceutical industry, Trevor has consulted for compani...

PURPOSE Artificial corneas or keratoprostheses such as the Boston keratoprosthesis (KPro) are being used more frequently to provide a clear corneal window in patients with severe corneal disease. A significant percentage of patients who undergo Boston KPro implantation require subsequent eyelid surgery. However, few articles in peer-reviewed literature evaluate the indication and outcome of eye...

PURPOSE To report a patient with refractory keratitis after a Boston type I keratoprosthesis treated with corneal collagen cross-linking (CXL). METHODS Case report. RESULTS A 29-year-old man with a history of chemical burn in the left eye underwent keratoprosthesis implantation. He developed infectious keratitis 4 months after surgery, which did not respond to topical antibiotics. The patie...

Scalds, which are burns attributed to hot liquids or steam, account for 33%-58% of all patients hospitalized for burns in the United States. Adults aged >/=65 years have a worse prognosis than younger patients after scald burns because of age-related factors and comorbid medical conditions, and they are subject to more extensive medical treatment than younger adults. To estimate the number of e...

Retrospective surveys of all hospitalized pediatric burns under the age of 15 years were conducted in 18 hospitals from 5 provinces and municipal cities of North China between 2001 and 2010. A total of 17,770 patients were included in this study. The epidemiological characteristics of hospitalized pediatric burns and influencing factors of length of hospital stay and hospitalization cost were a...