introduction: chemotherapy is recognized as a primary cancer treatment method, but despite its benefits, it causes side-effects. the most important of these side-effects are nausea and vomiting. given the simplicity of use of non-medicinal methods such as semi-sitting position, which can be performed by the patient alone, with the least effort and no side-effects, this method can be utilized to...

purpose: the aim of the present study was to detect the expression of p-glycoprotein (p-gp) and multi-drug resistance associated protein 1 (mrp1) in retinoblastoma tumors, and analyze the relationship between its expression, the clinico-pathological features and recurrence. methods: p-gp and mrp1 expression in formalin-fixed paraffin-embedded retinoblastoma bearing ocular tissue sections from 2...

Nearly 50 % of newly diagnosed colorectal cancer, affect people over 70 years of age. Inclusion of older patients in clinical trials has been extremely rare. As a result, there is debate on how to manage these patients because it is still unclear how to balance the therapeutic advantages and toxicities. For patients who do not have comorbid conditions, with performance status (P.S.) 0–1, treatm...

Doxorubicin, used in pediatric chemotherapy regimens, has cardiotoxic effects. Dexrazoxane is co-administrated with doxorubicin to prevent its cardiotoxicity. Here we have explored some alternative food or drugs to be used in absence of dexrazoxane since it’s not readily available in Iran at this time. Keywords: Pediatric, chemotherapy, doxorubicin, cardiotoxicity, dexrazoxane, Iran.

Background: Mucositis is a complex inflammatory response of the digestive system mucous membrane and it is also one of the most common painful side effects following chemotherapy in children with carcinoma. Developing to mucositis affects the patient's life severely and can lead to long – term hospitalization.Therefore, this study was conducted to evaluate the effect of chamomile mouthwas...

Introduction: Cancer is a global health problem. Taste change is one of the most common symptoms in cancer patients undergoing chemotherapy. Cancer patients often use Complementary and Integrative Medicine (CIM) to manage chemotherapy complications. Objective: This study aimed to evaluate CIM used by cancer patients to cope with chemotherapy-related taste alterations. Materials and Methods: T...

Diffusely increased glucose metabolic activity in the right and left ventricles using 2-deoxy-2-(F-18) fluoro-D-glucose positron emission tomography/computed tomography (18F-FDGPET/CT) and global left ventricular hypokinesia at echocardiography can be evident in acute myocarditis. But, there has been no case report that the ventricular 18F-FDGuptake remains unchanged even ...

Background: The global cancer incidence and the number of survivors are increasing. Therefore, it is necessary to pay more attention to the side effects of treatment. Aim: The aim of this study was to assess the effect of reflexology on the side effects of chemotherapy in cancer patients. Method: For finding the related articles, the researchers searched several databases including PubMed & P...

Abstract Background Tumor Lysis Syndrome (TLS) is an oncologic emergency that results from massive lysis of malignant cells. The incidence of TLS depends on the risk factors, such as baseline hyperuricemia, bulky tumor burden, elevated serum LDH, and elevated WBC. The objectives of the present study were to assess frequency of Tumor Lysis Syndrom in children with ALL in two methods of inducti...