the effect of non – pharmacologic pain management methods for venipuncture pain in school aged children in the center for thalassemia in the city of kerman     bageriyan s [1] , borhani f [2] *, abaszadeh a [3]     received: 12 sep, 2012 accepted: 20 nov, 2012   abstract   background & aims : establishing intravenous line (iv catheter) is one of the most common invasive procedures that cause pa...

background: thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. objective: to determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis b surface antibody (anti-hbs ab) following the last hbv vaccine injection. methods: this study was carried out on 215 thalassemic children who received t...

Patients and Methods: Ninety children with beta-thalassemia major (55 males and 35 females) with a mean age of 7.17±3.78 years (1-13 years) and age and sex matched control group of 60 healthy children (36 males and 24 females) with a mean age 6.98±3.66 years (1-13) years. Serum parathyroid hormone (PTH), serum total Calcium (Ca), serum phosphorus (P), serum alkaline phosphatase (ALP), serum 25-...

background: thalassemia/haemoglobinopathy is a hereditary disease with increased erythropoiesis and expansion of the bone marrow cavity. consequently, there is a reduction in trabecular bone tissue resulting in osteopenia/osteoporosis. the present study was performed to determine bone mineral density (bmd) in children and adolescents with major thalassemia and its correlation with serum ferriti...

An elevated tricuspid regurgitant jet velocity (TRV) is associated with hemolysis and early mortality in sickle cell disease, yet risk factors, clinical parameters, and mortality associated with this biomarker in thalassemia are poorly defined. This report summarizes the prevalence of an elevated TRV in 325 patients screened by Doppler echocardiography in the Thalassemia Clinical Research Netwo...

Objectives. Check with hematological data that the diagnosis and clinical grade of β-thalassemia intermedia can be established when a triplication genes alpha (αααanti 3.7) heterozygous are coherent. Methods. Retrospective study in which 73 patients Caucasian origin participated, who simultaneously showed tripling or quadrupling α β-thalassemia. Screening for most frequent α-thalassemia mutatio...

Background: Screening and counselling is the most effective way to prevent the birth of children with thalassemia major. An accurate and relatively less time-consuming protocol is necessary to screen large populations. Separating iron deficiency anaemia from thalassemia trait based on blood cell parameters has been used by hematologists for many years. We aimed to design a new approach to scree...

background: advances in treatment of thalassemia major have improved the life expectancy of the patients and therefore their quality of life as other chronic diseases. this study was conducted to assess health- related quality of life in these patients in guilan province. methods: in a cross-sectional study, thirty-one children, aged 8-12 years, with β-thalassemia major were interviewed in guil...

BACKGROUND Studies have shown that social capital is positively associated with health, and the association is context-based. Indigenous populations with poor access to health care largely depend on social capital for their health care needs. This study was conducted to explore the dimensions and types of social capital and its utilization by families with thalassemia for their health and well-...

AIM To investigate ophthalmologic findings in children with thalassemia major (TM) and compare the findings with healthy controls. METHODS In a cross-sectional study, 43 children with thalassemia major from pediatric hematology outpatient clinics from two university hospitals and age/sex matched 47 healthy children were included in the study. After a complete ophthalmic examination, tear func...