1Centro de Estudios Fotosintéticos y Bioquı́micos (CEFOBI-CONICET), Universidad Nacional de Rosario, S 2002 LRK Rosario, Argentina 2UB6, Instituto de Investigaciones Biotecnológicas (IIB INTECH), Avenida Intendente Marino Km 8200, CC 164 7130 Chascomús, Argentina 3Laboratory of Transcriptional Networks, Centre for Integrative Biology, University of Trento, 38123 Mattarello, Italy 4REQUIMTE, Depa...

Vitamin D is a lipid-soluble substance that has two forms, vitamin D2 (ergocalciferol) and D3 (cholecalciferol). UV light the main source of induces conversion 7-dehydrcholestrol to in skin. Food sources contain high amount are egg yolk, fish, liver. Several studies revealed wide prevalence deficiency Vit. among healthy population, addition, different diseases have relation with their inadequac...

1090-7807/ 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Michael J. Knight a,⇑, Risto A. Kauppinen a,b a School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol, BS8 1TU, United Kingdom Clinical Research and Imaging Centre, University of Bristol, 60 St Michael’s Hill, ...

BACKGROUND Vitamin D repletion with high doses of vitamin D is often recommended to patients and healthy subjects. The safety, especially concerning changes in urinary calcium excretion is of great importance. METHODS In a double-blinded, placebo-controlled study in 40 healthy volunteers, we examined the changes in mineral metabolism during supplementation with 3000 IU of oral cholecalciferol...

Hypocalcemia is one of the most frequent complications after total extracapsular thyroidectomy (TET). In most of cases it is a transient phenomenon. The aim of this study is to evaluate if and how the oral administration of calcium or calcium combined with D-vitamin could effectively prevent post-thyroidectomy hypocalcemia. A randomized prospective study was performed, recruiting 120 patients w...

BACKGROUND Vitamin D (VD) deficiency results in a worse prognosis in patients with chronic lymphocytic leukemia (CLL) and may affect the production of cytokines. Nonetheless, there is the lack of studies dealing with VD supplementation and its impact on chemokines in CLL patients. AIM The primary endpoint of our interventional study was to evaluate the effect of cholecalciferol supplementatio...

BACKGROUND Vitamin D deficiency is common among immigrants in the Nordic region. It may lead to osteomalacia with severe musculoskeletal pain. There are reports that vitamin D deficiency without osteomalacia may lead to pain but little is known of the effect of treatment. OBJECTIVE To investigate whether a moderate dose of cholecalciferol and calcium improves strength and pain in a group of v...

A 55-year-old woman developed an atraumatic sternum fracture during treatment with alendronate for osteoporosis. The woman received alendronate 70 mg in combination with cholecalciferol 5600 IU once weekly, as well as nonsteroidal anti-inflammatory drugs. After 4 years of treatment, following a dorsal flexion with no direct thoracic trauma, the patient suffered a fracture of the sternum, with a...