background vitamin d deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. it is also shown that vitamin d deficiency may result in chronic liver disease or liver cirrhosis. in this study, we aimed to systematically review the literature wherein the relationship between vitamin d deficiency and the severity of chronic liver disease or liver cirrhosis had...

BACKGROUND One of the major morphologic characteristics of hepatitis B is a hepatocellular regeneration which is induced by massive hepatocyte necrosis and associated with proliferative activity of hepatocytes. The purpose of this study is to document the proliferative activity of hepatocytes in various types of hepatitis B by immunohistochemical staining for proliferative cell nuclear antigen-...

Liver disease, particularly viral hepatitis, is increasingly common. The most frequent causes of long-term, or chronic, viral hepatitis are persistent infections with the hepatitis B or hepatitis C virus. Worldwide, 400 million people are chronic carriers of the hepatitis B virus [1]. Each year, between 500,000 to 1.2 million people die from progression of this viral infection, making it the 10...

BACKGROUND Carbohydrate 19.9 antigen (CA19.9) has been used in the diagnosis and followup of gastrointestinal tumours. The aim of this prospective longitudinal study was the evaluation of CA19.9 levels in patients with chronic hepatitis and hepatic cirrhosis hepatitis C virus and B virus correlated. MATERIALS AND METHODS 180 patients were enrolled, 116 with HCV-related chronic liver disease (...

understanding of the natural history of chronic hbv infection is useful for presenting the optimal management of chronic hbv infection. the aim of this study was to evaluate the natural history of chronic hepatitis b infection.in this cross sectional study, 219 untreated chronic hepatitis b patients from jan. 2010 to aug. 2012 were included. the subjects were classified in four groups based on ...

Primary liver cancer occurs mainly as a result of chronic liver disorders due to hepatitis virus infection. The important thing in preventing liver cancer is to prevent hepatitis virus infection and eliminate hepatitis virus in chronic hepatitis patients. In order to eliminate hepatitis virus in chronic viral hepatitis, therapies with interferon or recently introduced lamivudine are indicated f...

INTRODUCTION Hepatitis B and C coinfection is commonly seen in clinical practice. In coinfected individuals, high levels of hepatitis C viremia are often associated with low levels of serum hepatitis B DNA. Hepatitis B reactivation in hepatitis C-infected patients treated with pegylated interferon and ribavirin has been reported, but severe or fulminant reactivation is uncommon. Hepatitis C tre...

It is estimated that one-third of the world's population has been exposed to hepatitis B virus and that 300-400 million people have chronic hepatitis B. In areas of the world where hepatitis B infection is endemic, this chronic viral infection is a major cause of premature morbidity and mortality related to hepatocellular carcinoma (HCC) and complications of end-stage liver disease. Recent data...

Forty two cases of confirmed hepatitis C virus (HCV) infection with available liver histology were studied. Most patients, 23 of 42 (55%) had abnormal liver function tests but 19 of 42 (45%) had persistently normal liver transaminases (mean aspartate transaminase (AST) 24.1 IU/l, mean follow up 10 months). Histological examinations in the group with normal AST activities were normal in two of 1...