OBJECTIVES To examine the evidence derived from randomized controlled clinical trials on the efficacy and safety of omalizumab compared to placebo in controlling symptoms of chronic idiopathic urticaria/chronic spontaneous urticaria (CIU/CSU). DATA SOURCE The electronic databases PubMed, Medline, EMBASE, Biomed Central, The Cochrane Central Register of Controlled Trials (CENTRAL), Wiley, OVID...

AMA Mohammed J. Autologous serum therapy reduces the symptoms and antihistamine burden in patients with chronic urticaria. Advances Dermatology Allergology/Postępy Dermatologii i Alergologii. 2023;40(3):398-401. doi:10.5114/ada.2023.129009. APA Mohammed, (2023). Alergologii, 40(3), 398-401. https://doi.org/10.5114/ada.2023.129009 Chicago Jinan Q. 2023. "Autologous urticaria". Alergologii 40 (3)...

Intradermal injection of autologous serum and plasma elicit a cutaneous reactivity in almost 45-60% of patients with Chronic Idiopathic Urticaria (CIU). This reactivity is associated with the presence of auto antibodies against IgE or IgE receptors. This study was carried out to compare the cutaneous reactivity of autologous serum and plasma skin tests in a series of patients with CIU for diagn...

AIM The drugs of choice in the treatment of urticaria in children are H1-antihistamines. The aim of the study was to evaluate children with urticaria and define risk factors for requirement of high-dose H1-antihistamines in children with urticaria. MATERIAL AND METHODS The medical data of children who were diagnosed as having urticaria admitted to our outpatient clinic between January 2014 an...

BACKGROUND Autoimmune mechanisms are considered to play a significant role in chronic urticaria pathophysiology. Additionally, clinical experience emphasises the coexistence of chronic urticaria manifestation with thyroid autoimmunity. As the role of CTLA-4 polymorphism in autoimmune thyroid diseases is well proven we speculated on the possible role of this polymorphism in the background of chr...

Fexofenadine hydrochloride (FFH), chemically known as (±)-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl benzene aceticacid hydrochloride [1] is a active metabolite of terfenadine and is a second-generation histamine H1-receptor antagonist in piperidine-class drugs. These drugs are used in the treatment of seasonal allergic rhinitis, chronic idiopathic urticaria etc...

Background Treatment of Chronic Idiopathic Urticaria (CIU) may be challenging, as patients can be refractory to various treatments. This may be due to an autoimmune mechanism in its pathogenesis. CIU has been shown to be associated with autoantibodies to IgE or IgE receptor and with thyroid autoimmunity [1,2]. Treatments targeting this autoimmune pathogenesis are now being used, such as intrave...

Methotrexate has immunosuppressive effects and is administered for refractory chronic urticaria. We present a case of Pneumocystis jirovecii pneumonia in a patient with refractory chronic urticaria managed by low-dose weekly methotrexate treatment (total cumulative dose 195mg). Our study highlights the importance of providing prompt diagnosis and treatment of Pneumocystis jirovecii pneumonia in...

apply to them, it applying for 6 month. Results: All the patient improved their Urticaria between weeks 3 and fort of application of the drug, getting the control of the symptoms between the month 2 and 3 in the 5 patients, without requiring other drugs for their control, and remained asymptomatic for 3 and forth months discontinuity the product up to 6 months, not reactivity the Urticaria, the...

BACKGROUND Though autoimmune phenomena have been regularly associated with chronic urticaria in adults, data in children are sparse. AIM To describe our experience with children and adolescents with chronic urticaria and autoimmunity. METHODS AND RESULTS Of 187 patients referred for evaluation of chronic urticaria during a 7.5 year period, eight (4.3%), all females aged 7-17 years, had incr...