The prevalence of gallbladder injury in a traumatic event is rare, occurring only 1.9%-2.0% all abdominal traumas. Isolated injuries, without any damage to surrounding organs or tissues, are even less common. Presenting symptoms often nonspecific, and imaging modalities ultrasound (US) CT usually relied upon diagnose accurately. Identifying strategically treating cases injury, through reviewing...

OBJECTIVE Several interventions promote axonal growth and functional recovery when initiated shortly after central nervous system injury, including blockade of myelin-derived inhibitors with soluble Nogo receptor (NgR1, RTN4R) decoy protein. We examined the efficacy of this intervention in the much more prevalent and refractory condition of chronic spinal cord injury. METHODS We eliminated th...

conclusions generalized ligamentous laxity is an important predisposing factor for acute and chronic shoulder injuries in athletes. prescreening programs for beginners and rehabilitation shoulder programs for sports athletes at high risk are strongly recommended. results group a (with ligamentous laxity) consisted of 43 participants (36.4%) and group b (without ligamentous laxity) consisted of ...

PURPOSE The current study was designed to examine the antinociceptive effect of intrathecally administered capsaicin, a transient receptor potential vanilloid 1 receptor agonist, in a rat model of neuropathic pain induced by unilateral sciatic nerve chronic constriction injury. METHODS Male adult Sprague Dawley rats were randomly assigned to six groups, and all rats underwent unilateral sciat...

OBJECTIVES An 'information gap' has been identified regarding the effects of chronic disease on occupational injury risk. We investigated the association of ischaemic heart disease, hypertension, diabetes, depression and asthma with acute occupational injury in a cohort of manufacturing workers from 1 January 1997 through 31 December 2007. METHODS We used administrative data on real-time inju...

BACKGROUND The goal of this study was to determine whether advanced age affects mortality and incidence of neurological injury in patients undergoing surgical repair with hypothermic circulatory arrest in acute and chronic thoracic aortic pathology. METHODS AND RESULTS A university center audit was done of 523 consecutive patients (median age, 64 years; interquartile range, 56-71 years) betwe...

Inflammation is a characteristic feature of virtually all acute and chronic liver diseases. It intersects different pathologies from the early stages injury, when inflammatory burden mild-to-moderate, to very advanced disease, response intense drives multiple organ dysfunction failure(s). The current review describes most relevant features process in two clinical entities across disease spectru...

Tissue fibrosis and chronic inflammation are common causes of progressive organ damage, including progressive renal disease, leading to loss of physiological functions. Recently, it was shown that Toll-like receptor 2 (TLR2) is expressed in the kidney and activated by endogenous danger signals. The expression and function of TLR2 during renal fibrosis and chronic inflammation has however not ye...

To speed up the process of central nervous system (CNS) recovery after injury, the need for real-time measurement of axon regeneration in vivo is essential to assess the extent of injury, as well as the optimal timing and delivery of therapeutics and rehabilitation. It was necessary to develop a chronic animal model with an in vivo measurement technique to provide a real-time monitoring and fee...

Background—The goal of this study was to determine whether advanced age affects mortality and incidence of neurological injury in patients undergoing surgical repair with hypothermic circulatory arrest in acute and chronic thoracic aortic pathology. Methods and Results—A university center audit was done of 523 consecutive patients (median age, 64 years; interquartile range, 56 –71 years) betwee...