introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...

Chronic obstructive pulmonary disease (COPD) exhibits significant heterogeneity in its clinical presentation and rate of progression among affected individuals, owing at least part to differing morphologic abnormalities. Symptom assessment, spirometric evaluation, frequency respiratory exacerbations have traditionally been used determine severity guide management. ChestComputed Tomography (CT)...

Latent viral infection has been implicated in the pathophysiology of chronic obstructive pulmonary disease (COPD). Epstein-Barr virus (EBV) is known to be important in pulmonary fibrosis. The current authors hypothesised that EBV is associated with the pathogenesis of COPD. Sputum samples were collected from patients both during exacerbations of COPD and when stable. A control group of smokers ...

There is considerable evidence that an increased oxidative burden occurs in the lungs of patients with chronic obstructive pulmonary disease (COPD) and this results in an imbalance between oxidants/antioxidants or oxidative stress, which may play a role in many of the processes involved in the pathogenesis of COPD. These include enhanced proteolytic activity, mucus hypersecretion and the enhanc...

Chronic obstructive pulmonary disease (COPD) is a common and treatable in the general population, accounting for high morbidity mortality rates. In patients with severe COPD, hypoxemia main cause of complications such as hypertension (PH) right ventricle (RV) dysfunction. However, presence RV vascular structural functional changes may occur early stages even before significant or PH. Subclinica...

Cigarette smoking is the most prevalent risk factor for the development of adult-onset respiratory diseases associated with airflow obstruction, namely emphysema and chronic bronchitis, commonly called chronic obstructive pulmonary disease (COPD). Regrettably, childhood asthma does not reduce the likelihood of initiation of smoking [1] but it is not fully clear how smoking impacts pre-existing ...

Chronic obstructive pulmonary disease (COPD) is associated with a high clinical and economic burden the fourth leading cause of death in United States. The management patients COPD aims to minimize control symptoms, prevent exacerbations, improve quality life. We provide an illustrated case study female patient typical progression describe diagnosis, assessment, strategy, referring evidence see...

OBJECTIVES To determine if chronic pulmonary diseases adversely impact selected outcomes in hospitalised patients who have various allergic conditions including anaphylaxis. DESIGN A population-based cohort study. PARTICIPANTS A statewide hospital inpatient discharge database from Texas, USA, covering the years 2004-2007 was analysed. Patients with anaphylaxis and other allergic conditions ...