background and aims. a link between the occurrence of severe periodontitis and several systematic health changes including an altered lipid metabolism has been suggested. the aim of this study was to investigate the relationship between chronic periodontitis and serum lipid levels. materials and methods. thirty patients with chronic periodontitis (the community periodontal index of treatment ne...

BACKGROUND Obesity is considered as a strong risk factor of inflammatory periodontal tissue destruction. The purpose of this study is to determine presence of progranulin (PGRN) and high sensitivity C reactive protein (hs CRP) levels in serum and gingival crevicular fluid (GCF) in obese subjects with chronic periodontitis and to find an association, if any. MATERIAL AND METHODS 40 subjects (2...

BACKGROUND Different studies have implicated the exposure to systemic conditions in the aetiology of cardiovascular diseases like chronic inflammation including chronic periodontitis. AIM The present study has been conducted to examine whether biomarker sTNF-R was elevated in apical periodontitis as sTNF-R is a systemic marker of inflammation and has been identified as risk factors for cardio...

Objective. Our aim in this paper was to investigate the possible genetic association between three Ser563Asn, Leu125Val and Arg670Gly polymorphisms of the PECAM-1 gene and periodontitis. Methods. Genomic DNA was isolated from whole blood of 105 periodontal patient (52 with chronic periodontitis and 53 with aggressive periodontitis) and 101 healthy individuals. Samples were genotyped and analyze...

OBJECTIVE The emergence of periodontal medicine increased interest in defining the behaviour of peripheral blood cells in periodontitis subjects in comparison with healthy group. The aim of this study was to evaluate the levels of interleukin (IL)-8, tumour necrosis factor-α (TNF-α), IL-6 and IL-10 released by Escherichia coli lipopolysaccharide (LPS)-stimulated peripheral blood mononuclear cel...

Periodontitis is defined as a chronic infectious disease caused by periodontal bacteria. Chronic periodontal inflammation results in alveolar bone loss and periodontal supportive tissue, eventually leading to tooth loss. Type 2 diabetes mellitus is mainly characterized by hyperglycemia because of impaired action of insulin. Though the etiology of the two diseases is different, number of reports...

Periodontitis is an inflammatory disorder, initiated by the presence of bacterial plaque, which affects both periodontal ligament and bone that surrounds teeth. These ailments include cardiovascular disease, gastrointestinal colorectal cancer, diabetes insulin Alzheimer's as well respiratory tract disease adverse events pregnancy. In recent decades, several lines evidence have supported existen...

BACKGROUND Accumulating evidence suggests that acute and chronic infections with periodontopathogens are associated with an increased risk of cardiovascular disease. The objective of this study was to assess whether Tanerella forsythia and Porphyromonas gingivalis are associated with increased levels of atherogenic low-density lipoprotein (LDL), high-density lipoprotein, total cholesterol (TC),...

Background: Despite the large number of publications, there is still controversy among clinicians regarding the application of dental lasers to the treatment of chronic periodontitis. The purpose of this review is to analyze the peer-reviewed research literature to determine the state of the science concerning the application of lasers to common oral soft tissue problems, root surface detoxific...

Methods: Forty-five patients were included in the study. Of the 45, 30 had type 2 diabetes mellitus with chronic periodontitis (group 1A; poorly controlled group, n = 15, HbA1c ≥ 7% and group 1B; well controlled group, n = 15, HbA1c < 7%) and 15 were systemically healthy (group 2) with chronic periodontitis. Plaque index, gingival index, probing depth, clinical attachment loss, gingival bleedin...