Introduction. Radical procedures like calcanectomy and amputation performed for calcaneal osteomyelitis are regarded as effective in eradication of infection even though potentially functionally disabling. Bone sparing procedures offer better functional result at the expense of potentially worse infection control. The aim of the study has been to assess the influence of the surgical radicalism ...

BACKGROUND Although bone specimens were established 25 years ago as the gold standard for etiologic diagnosis of chronic osteomyelitis, recent studies suggest that nonbone specimens are as accurate as bone to identify the causative agent. We examined concordance rates between cultures from nonbone and bone specimens in 100 patients. METHODS Prospective study conducted at Hospital Universitari...

Three Chinese patients, one female aged 63 years, two males aged 52 and 54 years, respectively, all presented with chronic sclerosing sialadenitis (CSS) as the initial clinical manifestation, followed by IgG4-related sclerosing pancreatitis. The kidneys and lungs were involved in case 1. Moreover, enlargement of hilar lymph nodes was also noted in this patient. After steroid therapy, the clinic...

This study reports on the outcome of four patients having ileal pouch anal anastomosis after orthotopic liver transplantation for sclerosing cholangitis complicating ulcerative colitis. There were no deaths on follow up. Early postoperative bleeding was a complication of colectomy or rectal excision in three, one of whom developed hepatic artery thrombosis and the overall complication rate was ...

<p class="Noindentpara">Chronic sclerosing sialadenitis (CSS) or Küttner’s tumour, a rare benign condition affecting submandibular gland, is now believed to be localised type of IgG4-related disease. It presents as an asymptomatic swelling. Histopathology the gold standard for diagnosis. Here we discuss same in 55-year-old male presenting painless swelling.</p>

AIM To evaluate the course of group A streptococcal osteomyelitis associated with severe disease nowadays. METHODS Three consecutive cases of severe group A streptococcal disease with osteomyelitis in children that were documented in Beer Sheva, Israel are described in detail. RESULTS Two of the three cases were postvaricella. Early in the course of the disease, the presentation resembled t...

The objective of this study was to evaluate the clinical outcomes and safety clindamycin combination antibiotherapy for treatment erythromycin-resistant, lincosamide-susceptible bone joint infections caused by Staphylococcus spp. Between January 2010 September 2018, 46 patients with were treated 6 12 weeks. type infection prosthetic in 20 cases (43.5%), osteosynthetic device 15 (32.6%), chronic...

Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in cirrhosis and need for liver transplantation and reduced life expectancy. The majority of cases occur in young and middle-aged men, often in association with inflammatory bowel disease. The etiology of primary sclerosing cholangitis includes immune-med...

Subacute sclerosing panencephalitis is caused by persistent brain infection of mutated virus, showing inflammation, neurodegeneration, and demyelination. Although many factors are emphasized in the pathogenesis of subacute sclerosing panencephalitis, the exact mechanism of neurodegeneration remains unknown. Micro-RNAs are small, noncoding RNAs that regulate gene expression at the posttranscript...