PURPOSE The purpose of this study was to evaluate the association between the rennin-angiotensin system (RAS) inhibition and the risk of breast cancer (BC) recurrence and progression in N3 positive patients. METHODS The medical records of patients treated for N3 positive BC in Hacettepe Cancer Institute between 2005 and 2012 were evaluated. Angiotensin converting enzyme (ACE) inhibitors/angio...

1. Saran R, Bragg-Gresham JL, Rayner HC et al. Nonadherence in hemodialysis: associations with mortality, hospitalization, and practice patterns in the DOPPS. Kidney Int 2003; 64: 254–262 2. Ferguson AV, Kasting NW. Electrical stimulation in subfornical organ increases plasma vasopressin concentrations in the conscious rat. Amer J Physiol 1986; 251: 425–428 3. Smith PM, Beninger RJ, Ferguson AV...

Paraneoplastic syndromes result from secretion of hormones, peptides or cytokines by tumor or immune cross-reactivity between malignant and normal tissues. These conditions are rare in children, but when the clinical presentation of patients with a tumor is unusual, these syndromes should be emphasized. Extrarenal tumors with renin-secretion are rare in children. They may be related to paraneop...

Migraine and hypertension are common complaints and both have high prevalence worldwide. The comorbidity of migraine with hypertension is a common issue since 1913. Recent epidemiologic and population-based studies put some doubt regarding the association between migraine and hypertension, no association or even negative association was found by some authors. Authors who supported the positive ...

The present study focused on gaining a better insight into how subclinical mastitis at the gland level in dairy sheep and goats affects milk yield and compositional changes in relation to curd yield. Animals chosen for the study had one udder half infected with identified coagulase-negative staphyloccocci (CNS) species and the contra-lateral gland was free of bacteria. Udder halves were tested ...

Aqueous two-phase systems (ATPS) that are formed by mixing a polymer (usually polyethylene glycol, PEG) and a salt (e.g. phosphate, sulphate or citrate) or two polymers, and water can be effectively used for the separation and purification of proteins. The partitioning between both phases is dependent on the surface properties of the proteins and on the composition of the two phase system as ha...

Glycomacropeptide (GMP) is the hydrophilic 64-amino acid C-terminal glycopeptide released into cheese whey when kappa-casein is cleaved by chymosin. GMP exists as a mixture of different glycoforms due to the carbohydrates sialic acid (N-acetylneuraminic acid, NeuNAc), galactose (Gal), galactosamine and glucosamine attached by O-glycosidic linkages. GMP reportedly stimulates the release of chole...