hepatitis delta virus (hdv) infection results in more severe and even fulminant form of hepatitis b in co-infected cases. this study was designed to estimate the prevalence of anti-hdv positivity and the associated risk factors in patients with chronic hepatitis b virus infection in zahedan (iran). in this cross-sectional study a total of 440 consecutive patients with chronic hepatitis b virus ...

cirrhosis is the consequence of chronic liver disease. deleterious effects of oxidative stress on hepatocytes may be reflected in the erythrocyte membrane. naltrexone (ntx) has been shown to attenuate hepatocellular injury in fibrotic animal models. the aim of this study was to investigate the progressive effect of ccl 4 on the liver and whether the improvement of liver cirrhosis can be monitor...

conclusions co-occurrence of pbc with wd is rare, which can cause diffusely intrahepatic copper deposition. early liver biopsy and genetic testing are necessary for the diagnosis. the combination of ursodeoxycholic acid with zinc and sodium dimercaptopropane sulfonate is effective. introduction both primary biliary cirrhosis (pbc) and wilson’s disease (wd) can cause copper retention in the live...

conclusions it is concluded that most hbeag negative hepatitis b patients with serum hbv dna level of 2000-20000 iu/ml, persistent normal alt concentration, and no or mild liver damage on biopsy can be clinically managed as hbv inactive carriers. results two hundred forty-three hbeag negative hepatitis b patients were stratified into three groups based on to their hbv dna level including group ...

introduction: indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the indian subcontinent. the definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.case presentation: an indian origin one and half year old premorbidly normal male child presented with history of gradual di...

BACKGROUND Liver cirrhosis is a risk factor for necrotizing fasciitis (NF), and is associated with markedly worse outcomes than for NF among non-cirrhosis patients. Only limited, mostly single-center, data were reported to date on the epidemiology, clinical features, resource utilization and outcomes of NF among patients with cirrhosis. METHODS We studied a population-based cohort of adult ho...

OBJECTIVE To determine the relation between body mass index (BMI) and liver cirrhosis and the contribution that BMI and alcohol consumption make to the incidence of liver cirrhosis in middle aged women in the UK. DESIGN Prospective cohort study (Million Women Study). SETTING Women recruited from 1996 to 2001 in NHS breast screening centres and followed by record linkage to routinely collect...

BACKGROUND A minority of persons at risk develop liver cirrhosis, but knowledge of risk modulators is sparse. Several reports suggest that coffee drinking is associated with lower cirrhosis risk. METHODS We studied 125,580 multiethnic members of a comprehensive prepaid health care plan without known liver disease who supplied baseline data at voluntary health examinations from 1978 to 1985. S...

Context The prevalence of hepatitis C virus (HCV) reached its peak in 1994 and is expected to decrease significantly over the next few years. However, HCV-related cirrhosis continues to increase. Razavi et al predicted that decompensated cirrhosis will reach its peak in 2019. This translates into increased healthcare costs secondary to complications of cirrhosis. Patients with cirrhosis due to ...