the absence of the steroid. In both, controls as well as hormone-treated cultures, Chromatographie separation of the acid-soluble fraction revealed that 95 to 98% of the radioactivity was associated with phosphorylcholine and that only a small amount was present as either cytidine diphosphate choline or choline. The labeled material in the lipid fraction consisted mainly of phosphatidylcholine ...

Generally accepted features of alcoholic fetopathy are delayed maturation and retarded dendritic development of neocortex, hippocampus and cerebellum. The present study investigates the effects of a membrane stabilizing agent (CDP-choline) on Purkinje cells of chronically alcohol intoxicated newborn rat pups, employing a Golgi impregnation technique. Both quantitative and qualitative data indic...

Traumatic brain injury (TBI) is a heterogeneous syndrome that includes various types of trauma. About 10–15 % patients have severe TBI, accompanied by high rates disability and mortality. Currently, the methods intensive care from standpoint evidence-based medicine are widely used for their treatment. Along with care, comprehensive cytoprotective program using Neurocitin®, which contains citico...