The aim of the present study was to investigate the prevalence of dental anomalies in a group of patients with cleft lip and palate (CL/P) in the northeast of Iran. Ninety-one patients referring to the Cleft Lip and Palate Clinic of Mashhad Dental School were enrolled and classified into right CL/P, left CL/P, and bilateral CL/P groups. Photographs, dental casts, and panoramic and periapical ra...

OBJECTIVE To assess the application and safety of transoral robotic surgery in the pediatric airway. DESIGN An institutional review board-approved study. Experimental laryngeal surgery was performed on 4 pediatric cadaver larynxes as controls. Application of robotic equipment for laryngeal surgery was attempted on 5 patients. SETTING Tertiary care pediatric medical center. PATIENTS Five p...

OBJECTIVE The margin of a palatal cleft is a unique anatomical site since the palatal mucosa is continuous with the nasal or nasopharyngeal mucosa. The aim of this study was to compare the expression patterns of cytokeratins and basal membrane components of the mucosa in the area of the cleft. DESIGN Biopsies from the mucosa of the hard palate and from the cleft margin in the soft palate were...

PURPOSE The patients with cleft lip and palate have a higher risk of cervical vertebrae anomalies than do patients in general population. The aim of present study was to determine the prevalence of various upper cervical spine anomalies in different type of clefts. PROCEDURES Lateral cephalograms of 128 patients (66 males, 62 females) with cleft lip and palate, and 125 (60 males, 65 females) ...

150 Maxillary sinus hypoplasia (MSH) is the underdevelopment of maxillary sinus antrum and it is usually associated with other anomalies, such as uncinate process and infundibular passage. Hypoplasia is classified into three: Type I is mild hypoplasia, normal uncinate and infundibulum; Type II is significant hypoplasia with hypoplastic or absent uncinate and pathological infundibular passage; T...

Congenital cleft palate causes a serious obstacle to children with regard to language and eating function. The aim of the current study was to examine the clinical application of a type of palatoplasty that has a reduced impact on the maxillary growth and good function in velopharyngeal competence. A total of 37 patients with cleft palate were treated with levator veli palatini retropositioning...

Any type of aesthetic correction in dental practice is always a challenging task, especially when it is complicated with cleft lip and alveolus. Careful examination and correct decision making at early stage of treatment and multi disciplinary approach is always necessary for long term success. This paper described a multidisciplinary approach in managing a 19-year-old female patient with unila...

OBJECTIVE To achieve consistency and uniformity in reporting speech outcomes in individuals born with cleft palate with or without cleft lip using perceptual parameters that characterize their speech production behavior regardless of the language or languages spoken. DESIGN A working group of six individuals experienced in speech and cleft palate was formed to develop a system of universal pa...

Previous work suggested that cleft lip with or without cleft palate (CL/P) is genetically distinct from isolated cleft secondary palate (CP). Mutations in the Bmp target gene Msx1 in families with both forms of orofacial clefting has implicated Bmp signaling in both pathways. To dissect the function of Bmp signaling in orofacial clefting, we conditionally inactivated the type 1 Bmp receptor Bmp...