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BACKGROUND The morphological characteristics of coronary plaques in patients with stable versus unstable coronary syndromes have been described in vivo with intravascular ultrasound, but the relationship between arterial remodeling and clinical presentation is not well known. METHODS AND RESULTS We studied 85 patients with unstable and 46 patients with stable coronary syndromes using intravas...

BACKGROUND Despite its importance for acute stroke management, little is known about the underlying pathophysiology when patients with acute stroke are classified using clinical methods. OBJECTIVE To examine the relation between the magnetic resonance defined stroke subtype and clinical stroke classifications using diffusion weighted imaging (DWI), perfusion weighted imaging (PWI), and angiog...

Multiple endocrine neoplasia (MEN) are clinical inherited syndromes affecting different endocrine glands. Three different patterns of MEN syndromes can occur (MEN 1, MEN 2A, and MEN 2B). MEN syndromes are very rare, affect all ages and both sexes are equally affected. MEN 1 is characterized by the neoplastic transformation of the parathyroid glands, pancreatic islets, anterior pituitary, and ga...

A lacuna is an area of infarction within the territory of a single perforated artery. Lacuna patients may present with numerous clinical syndromes. Lacunae typically present with highly focal brain symptoms (1). The clinical expression of lacunar infarcts is related to their location. Lacunae are more frequent in the basal ganglia, internal capsule, pons, and corona radiate (1); therefore, cort...