Abstract A 35-year-old woman presented with a 4-year history of persistent pruritic rash affecting her upper and lower limbs, concerning to the patient for cosmetic reasons. She denied any precipitating factors reported no improvement use topical clobetasol propionate. Notably, mother had similar rash, which also developed in 30s continued progress over time. Physical examination revealed bilat...

Background Plasma cell balanitis (PCB) is a chronic inflammatory dermatosis of the glans penis and prepuce, typically presenting as discrete shiny bright red plaques. Research on PCB scarce, with case reports small series. The aetiology, incidence prevalence remain unclear. Circumcision considered treatment choice. Topical treatments such topical corticosteroids, calcineurin inhibitors, fucidic...

the enzymatic potential of the cultured plant cells can be employed for bioconversion purposes. plant enzymes are able to catalyze regio- and stereo-specific reactions, and therefore can be applied for the production of desired substances. the biotransformation of foreign substrates with suspension cells of peganum harmala was tested with (±) phenylethyl propionate. the callus cultures of pegan...

Background: Recent findings establish the 308 xenon chloride (XeCl) excimer laser (EL) to be a new option in the area of UVB phototherapy. Since the EL enables high radiant exposure of narrow-band (NB) UVB and precise targeting of affected skin, it appears to be a promising treatment for the prurigo form of atopic dermatitis (AD). Objectives: To investigate the efficacy and safety of the excime...

BACKGROUND There is evidence to indicate that peripheral glucocorticoid receptor (GR) function is reduced in major depression, and a possible molecular explanation for this is the impact of raised pro-inflammatory cytokines. The topical steroid vasoconstriction assay provides a convenient probe of peripheral GR function. The present study sought to assess the sensitivity of peripheral GRs in an...

Senderey E, Patel S. BMJ Case Rep 2017. doi:10.1136/bcr-2017-222235 Description A 64-year-old woman with no dermatological history presents with a rash over her left eyebrow for the past 3 months with associated itching. The patient also states she has a bruise on her scalp from an accidental injury 1 year previously that continues to be sore. She was previously seen by her primary care physici...

History A 12-year-old boy presented with a history of blistering due to trauma on both shins since birth. They healed with scarring and milia formation. The lesions mainly affected the shins and some occasionally appeared on the waist. They were mildly pruritic and were worse in the summer as well as being precipitated by trauma. There was also toenail dystrophy but his hair and teeth were norm...