Background: Pediatric malignancies are extremely heterogeneous yet account for only approximately 1% of all tumor diagnosis. These entities important to recognize because their clinical features non-specific and may mimic common disorders childhood .Pediatric solid malignant tumors clinico-biologically distinct. They more aggressive but usually respond satisfactorily chemotherapy. The advanced ...

Abstract Despite advances in solid tumor biology and oncology, pediatric adult primary brain cancer metastasis to the harbor dismal prognosis poor outcomes. One avenue overcome these clinical challenges is through developing robust immunotherapy better target tumor. Our group has previously shown that adoptive cellular therapy (ACT) provides therapeutic benefit against central nervous system (C...

conclusions the incidence of ipa in allogeneic hsct and patients with hematological malignancies was relatively high and a. flavus was the most common cause of pa. as molecular methods had higher sensitivity, it may be useful as screening methods in hsct and patients with hematological malignancies, or to determine when empirical antifungal therapy can be withheld. results seven (15.2%) out of ...

Background/Objective: Gliomas are the most common of the primary brain tumors and accounted for more than 40% of all central nervous system (CNS) tumors. Glioblastoma (GBM) remains one of the most fatal human malignancies because of its high angiogenic. Foretinib is an oral multikinase inhibitor that represented antitumor activity in clinical studies.  AURKA and AURKB genes have been shown to b...

Listeriosis is one of the CNS inflammatory diseases which is happened majority in the form of sporadic. Listeriosis is ingested with the food. Infection occurrence in an exposed person depends on the number of organisms ingested, the virulence of the organisms strain and the individual condition. It is known that Listeriosis has decisive importance as an infection which the cellular immunodefen...

Two cases of multiple concomitant CNS tumors of different histologic types are presented.  One was a case of neurofibromatosis type 2 (NF2) with 6 CNS tumors, and the other a case of 4 CNS tumors without any evidence of NF. To our knowledge, there is no report of concomitant occurrence of 6 CNS tumors in the medical literature. Neuroradiological  and operative findings are illustrated and discu...