نتایج جستجو برای: collagen synthesis
تعداد نتایج: 465864 فیلتر نتایج به سال:
Mesenchymal stromal cells (MSCs) have shown a high potential for cartilage repair. Collagen-based scaffolds are used to deliver and retain at the site of damage. The aim work was comparative analysis capacity MSCs from human adipose tissue differentiate into chondrocytes in vitro stimulate regeneration articular an experimental model rabbit knee osteoarthrosis when cultured on microheterogenic ...
we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.
OBJECTIVE To explore the influence of charred Gossamer urocteae (CGU) on the functions of primary cultured mouse oral fibroblasts and reveal its mechanism in wound healing. METHODS CGU was extracted with different solvents and ethanol extract (EE), ethyl acetate fraction (EF), n-butanol fraction (BF) and aqueous fraction (AF) were obtained. The effects of different fractions on the proliferat...
OBJECTIVE Vascular smooth muscle cell (VSMC) migration, proliferation, and collagen synthesis are key events involved in the pathogenesis of cardiovascular disease. Growth factors, such as platelet-derived growth factor (PDGF) and fibroblast growth factor, released during vascular injury plays a pivotal role in regulating these events. Curcumin (diferuloyl methane), a major component of the spi...
Acute exercise induces collagensynthesis in both tendon and muscle. Thisindicates an adaptive response in the connectivetissue of the muscle-tendon unit. However, it isnot known if regulation of collagen expression isdependent on the type of contraction performedby the muscle. Furthermore, the possibleinvolvement of collagen inducing growthfactors, such as transf...
In nongranulomatous fibrotic lung conditions, we have recently shown that early collagen synthesis by myofibroblasts occurs in an extracellular matrix rich in the proteoglycan versican. We hypothesized that versican is associated with the process of collagen synthesis resulting from chronic inflammation. In this study, we examined the localization of proteoglycans and collagen in the granulomat...
Longissimus muscle biopsies were obtained from forty bulls and steers representing Charolais, Simmental, Angus and Hereford breeds at 6, 9, 12, 15 and 18 months of age to evaluate the influence of age, breed and sex on the biosynthesis of muscle collagen. Blood samples were collected from each animal at each time period. The blood serum was harvested and assayed for concentrations of testostero...
PURPOSE Transforming growth factor (TGF)-beta has been implicated as the key mediator of proliferative vitreoretinopathy, but the cellular mechanisms by which TGF-beta induces extracellular matrix protein (ECM) synthesis are not fully understood. The current study was conducted to examine whether the mitogen-activated protein kinase (MAPK) pathway is involved in TGF-beta 2-induced collagen expr...
Clinical testing of the nutraceuticals glucosamine (glcN) and chondroitin sulfate (CS) has shown efficacy in providing relief from symptoms in osteoarthritic patients. In vitro and in vivo studies support existence of a synergistic relationship upregulating synthetic activity in chondrocytes. A combination of glcN and CS may also be useful as adjunct therapy in sports-related injuries if simila...
BACKGROUND/AIMS Halofuginone, an inhibitor of collagen synthesis, prevented and caused resolution of established hepatic fibrosis. A genomic approach in vivo was used to search for additional genes responsible for halofuginone mode of action. METHODS Fibrosis was induced in rats by thioacetamide (TAA) and evaluated by collagen type I gene expression and the levels of collagen, tissue inhibito...
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