Objective(s): Epidermolysis bullosa is one of the most important series of mechano-bullous heritable skin disorders which is categorized into four major types according to the layer that bullae forms within basement membrane zone. In dystrophic form of the disease, blisters are made in the sublamina densa zone, at the level of type VII collagen protein which produce anchoring fibrils. Type VII ...

The purpose of this study was to investigate the effects of basic fibroblast growth factor (bFGF) treatment on the proliferation and apoptosis of cultured gingival fibroblasts (GFs). Human GFs were isolated from the palatal gingival tissues of 16 healthy volunteers ranging in the age from 9 to 35 years old. Cultured GFs were subjected to the analyses for cell proliferation by ELISA assay, gene ...

PURPOSE To determine the influence of low-power laser (660 nm) on the collagen percentage and macrophages in skin wounds in diabetic rats. METHODS 30 male Wistar rats were used, distributed in two groups: laser treated diabetic (n= 15); untreated diabetic (n = 15). The diabetes was induced by intravenous injection of alloxan into the dorsal vein of the penis, at a rate of 0.1 ml of solution p...

A 49-year male patient with type 2 diabetes mellitus with diabetic foot syndrome was evaluated by comprehensive diabetic foot assessment. Photobiomodulation therapy (low-level laser therapy) was prescribed for neuropathic pain and symptoms with scanning and probe method for 10 sessions. Customized insoles were recommended for redistributing the plantar pressures and reducing stress on the diabe...

conclusions this study confirmed the efficacy of pw lllt on biomechanical strength, trabecular bone volume, callus volume, and osteoblast number of repairing callus in a complete tibial osteotomy animal model at a relatively late stage of the bone healing process. materials and methods this experimental study was conducted at shahid beheshti university of medical sciences in tehran, iran. we pe...

background: neuropathic pain (np) is one of the most suffering medical conditions that often fail to respond to certain pain therapy. although its exact etiology is still unknown the role of reactive oxygen species (ros) and oxidative stress were explored by many researchers. neuropathies either central or peripheral lead to painful condition as well as social and economic isolation, thus vario...

introduction: low back pain is one of the most common musculoskeletal disorders,which is prevalent among the public population. depending on the severity of the patients’ pain, different treatments are selected for them. few studies have addressed, so far, the therapeutic effects of laser in such pains and different results have been published in this regard. the aim of this study is to investi...

conclusions caffeic acid treatment reduced bacterial growth and resulted in a decreased number of colony formation. the simultaneous effect of caffeic acid and laser at three time courses showed a synergic effect in reducing colony formation compared to the control and caffeic acid, and laser alone. objectives the aim of this study was to investigate the effect of caffeic acid and low-power las...

Background: Periodontitis and rheumatoid arthritis (RA) share a number of clinical and pathologic features, one of which is the presence of the tumor necrosis factor alpha (TNF-α)-induced bone resorption that is involved in the pathogenesis of both. Objectives: To investigate the effect of TNF-α blockade on periodontal conditions in patients with active RA. Method: The periodontal statuses of 3...