primary choriocarcinoma of the uterine cervix is an extremely rare disease. the clinical diagnosis of cervical choriocarcinoma is difficult, because of its rarity and being non-specific abnormal vaginal bleeding the most common symptom. in the present report,the authors present a case of cervical choriocarcinoma, which was initially misdiagnosed as a cesarean section scar ectopic pregnancy. rem...

Patients diagnosed with molar pregnancy are treated by either suction curettage or hysterectomy, depending on their desire to preserve fertility. We use single-agent chemotherapy, preferably methotrexate, to treat low- or moderate-risk persistent trophoblastic tumors. High-risk patients who have metastatic disease are treated primarily with combination chemotherapy and, as indicated, adjuvant r...

Introduction Cancer is currently treated by a combination of therapies, including chemotherapy. As a side effect, chemotherapy is believed to suppress the host immune system. Combination of immunotherapy and chemotherapy has been reported to be correlated with improvement of survival. However this combination needs careful planning in order to achieve a synergistic effect. In this study we have...

background: oral mucositis is the chief complication of head and neck chemotherapy. the current study was conducted to evaluate hypozalix artificial saliva and propolis mouthwash efficacy for the prevention of chemotherapy-induced oral mucositis in leukemic patients. materials and methods: the present double-blind clinical trial was carried out on 72 patients, undergoing chemotherapy. the patie...

We evaluated the outcome of anti-leukemia chemotherapy on 42 patients with the high-risk myelodysplastic syndromes (MDS)-refractory anemia with excess of blasts (RAEB), 8 cases; RAEB in transformation (RAEB-T), 18 cases; chronic myelomonocytic leukemia (CMMOL), 6 cases; and leukemic transformation of MDS, 10 cases. The median age was 67 (range 20 to 84). As a remission-induction therapy, 35 pat...

BACKGROUND The combination of chemotherapy and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) currently has become the hotspot issue in the treatment of non-small lung cancer (NSCLC). This systematic review was conducted to compare the efficacy and safety of the synchronous combination of these two treatments with EGFR TKIs or chemotherapy alone in advanced NSCLC. M...

BACKGROUND Efficacy of second-line chemotherapy in platinum-pretreated non-small cell lung cancer (NSCLC) is poor. This study investigated efficacy of computed tomography-guided percutaneous fine-needle 5% ethanol-cisplatin intratumoral injection (CT-PFNECII) combined with second-line chemotherapy in patients with platinum-pretreated stage IV NSCLC. PATIENTS Between October 2011 and July 2013...

Standard treatment for colorectal cancer includes surgery, radiotherapy, and chemotherapy. Conventional chemotherapeutic agents used in such as 5-fluorouracil, capecitabine which is oral form of irinotecan, oxaliplatin. One the major challenges chemotherapy considered drug resistance. Drug resistance occurs many different mechanisms alteration tumor microenvironment, growth kinetics, genetic va...