The fields of metabolomics and metabonomics attempt to phenotype and quantify the vast array of metabolites present in biological samples. Reversed-phase liquid chromatography (LC) coupled with mass spectrometry (MS) is a valuable tool in the separation and identification of these compounds. Reversed-phase HPLC techniques cover a wide range of compounds. However, ionic and polar compounds such ...

An axi{symmetric problem for a penny{shaped crack bridged by bres is considered. The study is reduced to the analysis of a hy-persingular integral equation with respect to the relative crack{face separation over a circular domain occupied by crack. The special case of a large crack subjected to Mode{I loading is examined. A matched asymptotic expansions technique is used in order to estimate th...

Purpose – The purpose of this paper is to present an analysis of common mode oscillations of several kilohertz in electrical drive systems. The analysed oscillations occur especially in electrical drive systems with active front end (AFE), common DC link and long motor cables and are independent of the well-known reflection phenomenon. Owing to the resulting overvoltages, the motor isolation li...

In the medium and high power range (starting from about 5kW) mostly three-phase Solar inverter systems are used. The PWM-systems reduce the harmonics of the mains current but insert a high frequency voltage between the DC-link and the neutral point of the AC-side, which is called common mode disturbance voltage here. This voltage is shown to be a four-level signal whose amplitude is in the rang...

• Targeted covalent kinase inhibitors (TCKIs) are an emerging new class of TKIs. Over 50% methods use protein precipitation for treating TCKI samples. Reversed-phase LC is the separation technique used in almost all bioaakttical assays. 85% a triple quadrupole MS as detector TCKIs bioanalysis. High-resolution more qualitative investigations TCKIs. Deriving from targeted (TKIs), TKIs that covale...

This paper presents some aspects of building reprogrammable system using current mode gates. With this approach it is possible to extend system on a chip solutions into the area of mixed mode applications. CMOS current mode gates consume almost constant current from the power supply and therefore are suitable for mixed mode operations. Contrary to voltage mode digital gates, presented in the pa...

A minimal complexity version of component mode synthesis is presented that requires simplified computer programming, but still provides adequate accuracy for modeling lower eigenproperties of large structures and their transient responses. The novelty is that a structural separation into components is done along a plane/surface that exhibits rigid-like behavior, thus only normal modes of each c...

In this paper we demonstrate a simple temperature and strain discriminating sensor based on a single fibre Bragg grating inscribed by a femtosecond laser via the point-by-point technique. These gratings exhibit strong and extensive cladding mode structures and by simultaneously monitoring both the Bragg wavelength and a cladding mode spaced by ~ 40 nm from the Bragg peak, as a function of both ...

The wake transition of the flow around two circular cylinders placed in staggered arrangements with fixed streamwise separation of 5D and cross stream separation varying from 0D to 3D has been studied. The wake transition is compared to that of a single isolated cylinder. Linear stability analysis utilising Floquet theory and direct numerical simulations, using the spectral/hp element method we...

This paper proposes a novel method based on pulse width modulation techniques to reduce and control the common-mode voltage in three-phase multilevel inverters. Besides controlling the common-mode voltage, this method is capable of controlling capacitors voltages and load currents with low switching losses and harmonic contents. In fact, due to the existence of different pulse patterns and the ...