Viruses employ a variety of strategies to hijack cellular activities through the orchestrated recruitment of macromolecules to specific virus-induced cellular micro-environments. Adenoviruses (Ad) and other DNA viruses induce extensive reorganization of the cell nucleus and formation of nuclear Replication Compartments (RCs), where the viral genome is replicated and expressed. In this work an a...

PURPOSE To measure the intraretinal oxygen environment at different stages in the Royal College of Surgeons (RCS) rat model of retinal degeneration to determine whether changes in oxygen level are an important aspect of the disease. METHODS Oxygen-sensitive microelectrodes were used to measure oxygen tension as a function of depth through the retina of anesthetized, mechanically ventilated RC...

The passive ultra-high frequency (UHF) RFID is being increasingly employed in various applications. The low-cost, long range and high data rate features making it an outstanding choice in contactless identification. Although, passive tag performance is likely to be affected by water and metal, tag packages and special tag designs are developed to minimize the effect of the environment. Tag perf...

We investigated the capacity of Royal College of Surgeons (RCS) rat retinal pigment epithelial (RPE) cells to take up all-trans-retinol (ROL) (vitamin A) and to metabolize it into retinyl esters (RE). Cultures of RPE cells were established from RCS and control newborn rats. All-trans-ROL was delivered to the apical surface of the RPE monolayer. Retinoids were analyzed by high-performance liquid...

We present a systematic investigation of rotation curves (RCs) of fully hydrodynamically simulated galaxies, including cooling, star formation with associated feedback and galactic winds. Applying two commonly used fitting formulae to characterize the RCs, we investigate systematic effects on the shape of RCs both by observational constraints and internal properties of the galaxies. We mainly f...

INTRODUCTION In response to concerns about the decreasing rural health workforce, the Australian Government has funded a number of clinical schools in rural locations across Australia. The University of Melbourne established its Rural Clinical School (RCS) in 2000, at Shepparton, population 42,000, 175 km north of Melbourne, Victoria. The University of Melbourne also has three metropolitan-base...

INTRODUCTION The achievement of successful clinical research projects depends on multiple team members including Research Coordinators (RCs), who are the link between the researcher and the trial participants. The RCs main responsibility is to ensure that all research is conducted according to the appropriate protocols, regulations and guidelines. AIM Description of demographics, the role and...