BACKGROUND Lung volume reduction surgery is effective at improving lung function, quality of life, and mortality in carefully selected individuals with advanced emphysema. Recently, less invasive bronchoscopic approaches have been designed to utilize these principles while avoiding the associated perioperative risks. The Endobronchial Valve for Emphysema PalliatioN Trial (VENT) posits that occl...

RATIONALE Interlobar fissure integrity has previously correlated with responsiveness to endobronchial lung volume reduction therapy in patients with advanced emphysema. OBJECTIVE This report summarises the effect of interlobar fissure integrity on responses to treatment with a novel endoscopic tissue sealant (AeriSeal emphysematous lung sealant (ELS)) that collapses hyperinflated lung. METH...

Khí phế thũng thùy phổi bẩm sinh (Congenital Lobar Emphysema - SLE) được biết đến như là căng chướng quá mức sinh, đặc trưng bởi dấu hiệu tăng kích thước của phổi. Hầu hết các trường hợp biểu hiện ngay trong tháng đầu đời; triệu chứng suy hô hấp điển hình. Những nhẹ thường bị bỏ qua và bệnh có thể ở trẻ lớn hơn song hiếm. CLE liên quan với một phần hoặc toàn bộ quản bít tắc, hệ quả (a) khiếm kh...

BACKGROUND AND PURPOSE Remote parenchymal haemorrhage (rPH) after intravenous thrombolysis is defined as hemorrhages that appear in brain regions without visible ischemic damage, remote from the area of ischemia causing the initial stroke symptom. The pathophysiology of rPH is not clear and may be explained by different underlying mechanisms. We hypothesized that rPH may have different risk fac...

INTRODUCTION Endoscopic lung volume reduction has been developed as a therapeutic option for advanced emphysema. Six-month results following treatment with endoscopic thermal vapor ablation (InterVapor; Uptake Medical, Tustin, CA) were described previously, and here we report observations from the 12-month assessment. METHODS Two multicenter, international, single-arm trials of InterVapor (un...

Background: Spontaneous pneumomediastinum (SPM) and subcutaneous emphysema are rare findings in children. Various etiologies have been reported for SPM, such as foreign body aspiration in infants, especially in those aged less than three years. In addition to the complications associated with foreign body aspiration, SPM may also become a life-threatening condition if left untreated. In the pre...