Two-component signaling pathways based on phosphoryl group transfer between histidine kinase and response regulator proteins regulate environmental responses in bacteria, archaea, plants, slime molds, and fungi. Here we characterize a mutant form of DCC-1, a putative histidine kinase encoded by the NCU00939 gene of the filamentous fungus Neurospora crassa. We show that this protein participates...

In Saccharomyces cerevisiae, Nce102 encodes a 173 amino acid transmembrane protein, which acts as a key player in eisosome assembly and plasma membrane organization. Here, we describe the characterization of Nce102 homologue in the human pathogen, Aspergillus fumigatus. Our results demonstrated that AfuNce102 is continuously expressed during fungal growth. In addition, microscopic examination o...

Calpains are ubiquitous and well-conserved proteins that belong to the calcium-dependent, non-lysosomal cysteine protease family. In this study, 8 putative calpains were identified using Pfam domain analysis and BlastP searches in M. oryzae. Three single gene deletion mutants (ΔMocapn7, ΔMocapn9 and ΔMocapn14) and two double gene deletion mutants (ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7) were obt...

Camellia oleifera is the native economic edible oil tree in China and anthracnose occurs commonly its producing areas. We previously found that ubiquitin-like CfAtg8-related autophagy essential for pathogenicity of Colletotrichum fructicola, major pathogen on C. oleifera. The aim this study to further elucidate roles pathogenesis fructicola. Based BLAST_P analysis reverse genetics, we identifie...

In cultures of Penicillium brevicompactum grown on Czapek-Dox agar or on circles of dialysis membrane placed on Czapek-Dox agar, brevianamides A and B first appeared after conidiation had begun. The presence of these brevianamides imparted a yellow-green fluorescence to the penicilli and to the upper section of the conidiophores of actively conidiating cultures. Experiments with replacement cul...

An unusual case is presented featuring chromoblastomycosis lesions localised in three different sites. The patient was a 52-year-old male farm worker from Barra do Corda, State of Maranhão, Brazil, who had had the disease for 2 years. Physical examination revealed extensive plaques situated on the left leg, left arm, forehead, and on the left side of the face. Direct examination of biopsies sho...

We have isolated three novel strains of Trichoderma (two T. harzianum and one T. atroviride) from wild mushroom and tree bark, and evaluated their biocontrol potential against Sclerotium delphinii infecting cultivated cotton seedlings. T. harzianum strain CICR-G, isolated as a natural mycoparasite on a tree-pathogenic Ganoderma sp. exhibited the highest disease suppression ability. This isolate...

’ ~ ~ T c ~ ~ ~ ~ Lnd MITCHELL 1952). Its phenotype is characterized by a long lag period, slow growth and defects in the cytochrome system during the early growth period. Older poky cultures recover to a considerable extent, approaching, but not attaining, either the wild-type growth rate or normal concentrations of the cytochromes (HASKINS, TISSIERES, MITCHELL and MITCHELL 1953; MITCHELL, MIT...