background: cutaneous malignancies are common in dermatologic practice. due to their relation to sun exposure the characteristics of these malignancies can differ in various geographic locations. this study intends to determine the characteristics of surgically treated cutaneous malignancies and various surgical modalities that have been applied. methods: this was a retrospective study of patie...

AIM Human papilloma virus (HPV) types 16 and 18 have been associated with neoplastic conditions of the conjuctiva. However, the presence of this virus has not been reported in non-neoplastic disorders of the external eye nor has it been studied in normal conjunctival tissues. METHODS Ninety six paraffin embedded tissue specimens with neoplastic and non-neoplastic lesions and 19 conjunctiva sa...

OBJECTIVES The aim of the audit was to determine the common orbital diseases necessitating orbital exenterations at Sekuru Kaguvi Hospital (SKH) between January and December 1999 and recommend ways of reducing the numbers of procedures done annually. DESIGN Retrospective cross sectional study. SETTING Department of Surgery, Parirenyatwa Hospital, University of Zimbabwe. SUBJECTS 23 patien...

Author Contributions:Dr Loprinzi had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Loprinzi, Brodowicz. Acquisition, analysis, or interpretation of data: Loprinzi, Sengupta, Solomon, Ramulu. Drafting of the manuscript: Loprinzi, Brodowicz. Critical revision of the manuscript for...

Changes in Salivary Antioxidants Patients with Oral Squamous Cell Carcinoma: Systematic Review Study and Meta-Analysis

Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva. Over the past three decades only fo...

Background: Carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. There are a number of suspected genetic or environmental etiologies. Human papilloma virus (HPV) is said to be a major etiology in areas with high incidence of esophageal carcinoma, while it is hardly detectable in low incidence regions. This study was designed to evaluate the prevalence of HPV in ...

objective(s): similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. reprogramming-related transcription factors, also known as yamanaka factors (oct4, sox2, klf4, and c-myc), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. long non-co...